Wen Chen
Instructor
Division of Molecular Cardiology
1901 South First Street, VA Bldg. 205
Temple,
Texas 76504
Phone: 254-743-1213
Fax: 254-743-0165
Email: wen.chen@medicine.tamhsc.edu
Curriculum Vitae
(PDF)
Education and Post-Graduate Training
B.S. Nanchang University (Biology), Nanchang, China, 1997
M.S. China Agricultural University (Biochemistry and Molecular Biology), Beijing, 2000
Ph.D. Peking University (Biochemistry and Molecular Biology), Beijing, China, 2003
Dissertation Title: Proteomics Study on the Senescent and Demented Postmortem Human Brains.
Teaching Interests
Selected Publications
- Chen W, Ji JG, Zhao R, Ru BG. Comparative Proteome Analysis of Human Temporal Cortex Lobes by Two-Dimensional Electrophoresis and Identification of Selected Common Proteins. Neurochemical Research 2002; 27(9): 871-81.
- Chen W, Ji JG, Ru BG. Comparative Proteome Analysis of Human Corticobasal Degeneration Brain with Normal Control Ones by Two-dimensional Electrophoresis and Identification of Selected Protein Spots. In: Proceedings of China Medical and Pharmaceutical Biotechnology 2002 Academic Conference, 2002: 155-60.
- Chen W, Ji JG, Xu XM, He SZ, Ru BG. Proteomic Comparison between Human Young and Old Brains by Two-Dimensional Gel Electrophoresis and Identification of Proteins. International Journal of Developmental Neuroscience 2003; 21(4): 209-16.
- Chen W, Ji JG, Ru BG. A Case Study of Corticobasal Degeneration at the Proteome Level. Journal of Neuropsychiatry and Clinical Neurosciences 2005; 17(3): 364-71.
- Schwarz K, Iolascon A, Verissimo F, Trede NS, Horsley W, Chen W, Paw BH, Hopfner KP, Holzmann K, Russo R, Esposito MR, Spano D, De Falco L, Heinrich K, Joggerst B, Rojewski MT, Perrotta S, Denecke J, Pannicke U, Delaunay J, Pepperkok R, Heimpel H. Mutations affecting the secretory COPII coat component SEC23B cause congenital dyserythropoietic anemia type II. Nature Genetics 2009; 41(8): 936-40.
- Chen W, Paradkar PN, Li LT, Pierce EL, Langer NB, Takahashi-Makise N, Hyde BB, Shirihai OS, Ward DM, Kaplan J, Paw BH. Abcb10 physically interacts with Mitoferrin-1 (Slc25a37) to enhance its stability and function in the erythroid mitochondria. Proc. Natl. Acad. Sci. USA 2009; 106 (38): 16263-8. (Accompanied commentary: Andrews NC. ABCs of erythroid mitochondrial iron uptake. Proc. Natl. Acad. Sci. USA 2009; 106 (38): 16012-3.)
- Chen W, Dailey HA, Paw BH. Ferrochelatase forms an oligomeric complex with mitoferrin-1 and Abcb10 for erythroid heme biosynthesis. Blood 2010; 116 (4): 628-30.
Specialty Training/Board Certifications
- Research Associate in Structure Biology and Mass Spectrometry Facility, Skirball Institute of Biomolecular Medicine, New York University Medical Center, New York, USA, 2004-2006
- Research Fellow in Hematology, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Harvard University, Boston, USA, 2006-2011
National Service/Recognition
- 1993-1997 Winner of Scholarships for Outstanding students, Nanchang University, Nanchang, China
- 2002 Graduate Award for Excellent Ph.D. candidates, Peking University, Beijing, China
- 2002 Tingmei Fellowship, Peking University, Beijing, China
- 2002 Excellent Research Article Award, China Medical and Pharmaceutical Biotechnology Society, China
- 2003 Jiuyuan Research Award, Fudan University Jiazhen Tan Foundation, China
- 2004 Outstanding Poster Award, New York University Medical Center, NY
- 2004 Scientific and Technological Advancement Award, Ministry of Education in Chin
- 2009 Competitive Travel Award from Federation of American Societies for Experimental Biology
- 2009 Research Excellence Award, Brigham and Women’s Hospital in Harvard Medical School, MA
- 2010 Competitive Travel Award from Gordon Research Conference
