January
- From the Dean
- College News
- Faculty
- Students
- Administration
- Basic Science
- Clinical Science
- Academic Medicine
From the Dean
Colleagues, Faculty, Staff and Students,
A new year is upon us, and I urge you take a moment to reflect upon all that has been achieved and to consider the challenges ahead. We ended the year by recognizing the outstanding work of our faculty on December 15 and 16, at the Bryan and Temple campuses, and I want to once more highlight the good work done by the awardees.
The Excellence in Research Award winners were Helene L. Andrews-Polymenis, D.V.M., Ph.D. (Junior Investigator) and James E. Samuel, Ph.D. (Senior Investigator), both of the Department of Microbial and Molecular Pathogenesis.
Distinguished Teaching Awards in Basic Science were presented to Gerald D. Frye, Ph.D. of the Department of Neuroscience and Experimental Therapeutics and David N. McMurray, Ph.D. of the Department of Microbial and Molecular Pathogenesis. Distinguished Teaching Awards in Clinical Science were presented to Rachel Bramson, M.D. of the Departments of Humanities and Family & Community Medicine and William Koss, M.D. of the Department of Pathology.
Outstanding Staff Award winners were Jane S. Miller of the Department of Microbial and Molecular Pathogenesis and Mindy Holster of the Dean’s Office. Join me in once again congratulating the hard work and dedication these folks have demonstrated for the College of Medicine.
I would also like to add that Ms. Ellen Weichert’s title is now Assistant to the Dean and to the Vice President for Clinical Affairs, as she coordinates the multiple obligations attendant to these posts. Ellen will continue to serve the Dean’s Office from the Bryan campus.
We have much to do in the coming months in addition to the daily rigors of medical education. Legislative happenings and our preparations for LCME continue to occupy a great deal of time and effort, and we remain positive in light of our busy workload. As more information becomes available from the Legislature, we will continue to keep you updated.
We also have much to look forward to, including our annual Mini-Medical School, the opening of the Medical Education and Research Building on the Bryan campus, Match Day and Commencement for the Class of 2011.
The college’s 7th Annual Mini-Medical School kicked off January 20 and will run every Thursday evening for six weeks. This popular community outreach program showcases the research and knowledge of our faculty and allows Bryan-College Station residents to hear current health and wellness topics from local experts. For more information about the 2010 Mini-Medical School, along with a list of speakers and topics, visit the Mini-Medical School website. Also, mark your calendars for the Class of 2011 Match Day on Thursday, March 17 and Commencement on Saturday, May 21.
Looking forward to 2011,
T. Samuel Shomaker, M.D., J.D.
The Jean and Thomas McMullin Dean of Medicine and
Vice President for Clinical Affairs for the Texas A&M Health Science Center
Dates to Remember
- Mini-Medical School 2010: Thursdays, January 20-February 24, 6-7:30 p.m., HPEB, LL lecture hall
- Dean’s Bi-Monthly Staff Meeting: January 25, 9-10:30 a.m., all locations
- Basic Science Department Chairs Meeting: January 27, 12-1:30 p.m., 3047B HPEB and 407C MEC
- Executive Committee Meeting: February 3, 3-4 p.m., all locations
- Dean’s Bi-Monthly Staff Meeting: February 8, 9-10:30 a.m., all locations
- Dean’s Bi-Monthly Staff Meeting: February 22, 9-10:30 a.m., all locations
College News
Round Rock Staff Gives Helping Hand to Children
On December 13, 2010, staff, faculty and students of the Round Rock campus delivered toys and games to the children at Helping Hand Home for Children in Austin. Helping Hand Home helps children overcome the effects of severe abuse and neglect in a safe, therapeutic environment. Many thanks to all for helping the children!
In Print and On Air:
The New York Times and The Texas Tribune recently noted Bryan, specifically its Biotech Corridor, (and its partnerships with the Texas A&M System and the Research Valley Partnership) as an emerging place in pharmaceuticals. Corresponding publications appeared in the Bryan-College Station Eagle and on KBTX.
LRC Receives Instructional Tech Grant for Second Time
For the second year in a row, the College of Medicine Learning Resources team received a Classroom Instructional Technology Matching Grant from the Texas A&M University Vice President and Associate Provost for Information Technology on December 15, 2010. The team included: Dr. Gale Hannigan, Bobbie Ann White, Bradley Perrin, Pam Baker, Drew Davenport and Jan Hubbell.
From 13 proposals totaling $184,000, the Learning Resources proposal was one of a few selected. The grant was fully funded for $2,145 and will be used to purchase a media receiver and display.
A media receiver attached to a large public display monitor will allow students to quickly queue their audio or video selection and play it on demand. This instant queue media center is a valuable option for watching educational “on demand” content, accessing web content, providing small groups a remote classroom, and promoting additional educational tools and opportunities.
Faculty
In Print and On Air
Simmons Featured in CNN Health Article
John Simmons, M.D., an Assistant Professor of Family & Community Medicine and Texas A&M Physician in College Station, was featured in an article re: modifying exams for obese patients on CNN’s Health.com on January 14.
Reddy Published in Journal of Neuroscience
On January 12, 2011, Associate Professor D. Samba Reddy, Ph.D. published a paper titled “Development and Persistence of Limbic Epileptogenesis Are Impaired in Mice Lacking Progesterone Receptors” in the Journal of Neuroscience. The paper reports a novel role of progesterone receptors as crucial mediators in the development of epileptogenesis, whereby a normal brain becomes progressively epileptic because of precipitating factors.
“This is one small part of the pathophysiology of epilepsy,” said Dr. Reddy. “The next step is to use a lead target to disrupt the pathway to prevent or retard epilepsy, which affects an estimated 1 million women in the United States.”
The work was supported by a National Institutes of Health Grant.
“We find when we inhibit the expression of the protein PR in the hippocampus, we retard the epilepsy development and we also reduce its persistence weeks after induction of this chronic brain condition”. "It's very exciting. I truly see this as an advance in our research,” said Dr. Reddy, a chartered member of NIH study section and lead author of the study. This study was co-authored by graduate student Ashwin Mohan and assisted by a team of expert collaborators/colleagues.
Students
Pappalardo Receives First TBSI Graduate Fellowship
On December 14, 2010, College of Medicine graduate student Dana Pappalardo was awarded the first Texas Brain & Spine Institute Graduate Fellowship in Neuroscience. This fellowship is awarded to an advanced graduate student in the Neuroscience degree program and covers the student’s stipend and tuition.
For the inaugural fellowship, there were 11 eligible students from the Texas A&M Health Science Center and the Texas A&M University Institute for Neuroscience.
The TBSI Fellowship will accept applications in 2011. See more at news.tamhsc.edu.
Student Holiday Service Activities
In fine style, College of Medicine students collected gifts for clients at Bryan-College Station’s Twin City Mission, sang carols at St. Joseph’s Regional Hospital and rocked out with the residents at Crestview Retirement Community in Bryan—all on December 10, 2010. See more photos at the College of Medicine facebook page. Many thanks to Wal-Mart in Bryan, Kroger in Bryan and TAMSA who provided money, toys and refreshments for the events.
Baby Gear Donation Event a Success
College of Medicine students in the Obstetrics and Gynecology Interest Group organized a drive for baby items in December to benefit the Prenatal Clinic in Bryan and ABC Women and Children’s Clinic in College Station. The drive was held across the Health Science Center locations in College Station was a great success thanks to everyone’s participation. The group raised nearly a $1,000 in supplies and gift cards over a two-week period.
Administration
2010 Service Award Winners
The 2010 service and excellence awards were presented on December 15 and 16, 2010, at the Bryan and Temple campuses, respectively. Congratulations to the teaching, research and service award recipients!
Excellence in Research Awards
Helene L. Andrews-Polymenis, D.V.M., Ph.D.
James E. Samuel, Ph.D.
Distinguished Teaching Awards
Basic Science:
Gerald D. Frye, Ph.D.
David N. McMurray, Ph.D.
Clinical Science:
Rachel Bramson, M.D.
William Koss, M.D.
Outstanding Staff Awards
Jane S. Miller
Mindy Holster
Weichert Adds Duties, Title Change
As of December 10, 2010, Ms. Ellen Weichert’s title is now Assistant to the Dean and to the Vice President for Clinical Affairs. Ms. Weichert will continue to serve the College of Medicine’s Dean’s Office from her post at the Bryan campus.
Basic Science
HUMANITIES IN MEDICINE
Medicine and Humanities Consultations 2011
February 14, 2011: Marilyn Freimuth, Ph.D., presents “Behavioral Addictions: Choice or Disease”
March 28, 2011: Alma Golden, M.D., presents “Ethical Issues of Public Health on Family Reproductive Patterns”
May 2, 2011: Ed Eckenfelds, M.D., presents “Compassion and the Professions: The Skipjack Project”
For additional information, contact the Dept. of Humanities in Medicine at 979-845-0755.
Consultations are held in The Longhorn Room of The Stagecoach Inn in Salado, Texas from 1-6 p.m. We anticipate the approval of four hours physician Continuing Medical Education credit, Continuing Nurses Education credit and social worker Continuing Education Units for each consultation.
MICROBIAL & MOLECULAR PATHOGENESIS
Recent Publications
Amminikutty Jeevan , Teizo Yoshimura, Lan H. Ly, Vijaya R. Dirisala and David N. McMurray. Cloning of guinea pig IL-4: Reduced IL-4 mRNA after vaccination or Mycobacterium tuberculosis infection. Tuberculosis 2010, in press.
Presentations, Conferences and Meetings
Dr. David McMurray traveled to New Delhi, India, from December 13-18, to attend an international tuberculosis symposium sponsored by the International Centre for Genetic Engineering and Biotechnology (ICGEB) entitled “TB Diagnostics: Innovating to make an impact”. He was invited to chair one of the scientific sessions.
Dr. James Samuel traveled to Alexandria, Virginia, from December 12-13, to attend the PATRIC SWG Meeting at the Virginia Bioinformatics Institute at Virginia Tech.
Awards
Dr. David McMurray received an Award Notice from NIH for a one-year, co-cost extension on his R01 AI15495-27 grant.
Dr. Katja Mertens received an Award Notice from NIH for a R03 grant entitled, “Development of Site-Specific Mutagenesis in Coxiella burnetii.”
Dr. David McMurray received the COM Distinguished Teaching Award.
Dr. Helene Andrews-Polymenis received the COM Excellence in Research Award (Junior Investigator).
Dr. James Samuel received the COM Excellence in Research Award (Senior Investigator).
Ms. Jane Miller received the COM Outstanding Staff Member Award.
Service
Dr. McMurray has been invited to serve a three-year term on the Editorial Board of the British Journal of Nutrition.
MOLECULAR & CELLULAR MEDICINE
Recent Publications
Su, S.-C., Maxwell, S.A., and Bayless, K.J. (2010)Annexin 2 regulates endothelial morphogenesis by controlling AKT activation and junctional integrity. J Biol Chem. 24(52):40624-40634. [Epub 2010 Oct. 13]
Huang, Z., Lu, Y., Majitha, R., Shah, J., Meissner, K., Matthews, K.S., Bondos, S.E.†, and Lou, J.† “Size dictates mechanical properties for fibers self-assembled by the Drosophila Hox transcription factor Ultrabithorax” (2010) Biomacromolecules, 11(12): 3644-3651 [Epub 2010 Nov 3].
Ashley, P., and Dobin, S. (2010) PS1-12: Use of Tumor Registry to Obtain Family History Information. Clin Med Res. 8(3-4):191-192.
Hai, B., Yang, Z., Millar, S.E., Choi, Y.-S., Taketo, M.M., Nagy, A., and Liu, F. (2011) Wnt/β-catenin signaling regulates postnatal development and regeneration of the salivary gland. Stem Cells and Development. 11:1793-1801. [Epub 2010 Sep 10].
Xie, R., Nguyen, S., McKeehan, W.L., and Liu, L. (2010) Acetylated microtubules are required for fusion of autophagosomes with lysosomes. BMC Cell Biol. 11:89 [Epub 2010 Nov 22].
Wang, J., Greene, S.B., Bonilla-Claudio, M., Tao, Y., Zhang, J., Bai, Y., Huang, Z., Black, B.L., Wang, F,, and Martin, J.F. (2010) Bmp signaling regulates myocardial differentiation from cardiac progenitors through a MicroRNA-mediated mechanism. Dev Cell. 19(6):903-912
Vanderlaag, K., Su, Y., Frankel, A.E., Burghardt, R.C., Barhoumi, R., Chadalapaka, G., Jutooru, I., and Safe, S. (2010) 1,1-Bis(3'-indolyl)-1-(p-substituted phenyl)methanes induce autophagic cell death in estrogen receptor negative breast cancer. BMC Cancer. 10:669.
Sawant, D.A., Tharakan, B., Adekanbi, A., Hunter, F.A., Smythe, W.R., and Childs, E.W. (2011) Inhibition of VE-Cadherin Proteasomal Degradation Attenuates Microvascular Hyperpermeability.Microcirculation. 18(1):46-55.
Gao, S., Wu, H., Wang, F., and Wang, Z. (2010) Altered differentiation and proliferation of prostate epithelium in mice lacking the androgen receptor cofactor p44/WDR77. Endocrinology. 151:3941-3953.
Presentations
Dr. Tina Gumienny presented ”Molecular characterization of TGF-beta regulation by multiple intracellular vesicle trafficking processes in C. elegans” which was co-authored by Kathy Beifuss at the 50th Annual Meeting of the American Society for Cell Biology in Philadelphia, PA on December 11-15, 2010.
Grants
Dr. Tina L. Gumienny was awarded a Beginning Grant-In-Aid from the American Heart Association-South Central Affiliate for a grant, $140,000 from 1/1/11 to 12/31/12, entitled “Molecular and cellular regulation of TGF-beta by glypican in C. elegans.”
Stephanie Green, Ph.D. with Dr. James Martin’s lab has been awarded a spot on a postdoctoral training grant though the Department of Molecular Physiology and Biophysics at Baylor College of Medicine.
Travel Grant
Yan Bai in Dr. James Martin’s lab received a Student Travel Grant from the Office of Research and Graduate Studies for travel support to the Mechanisms of Cardiac Growth, Death, and Regeneration Conference on February 22-27, 2011 at the, Keystone Symposia in Keystone, Colorado.
Travel Scholarship
Ye Tao, Ph.D. in Dr. James Martin’s lab was awarded a Keystone Symposia scholarship to the upcoming meeting on Mechanisms of Cardiac Growth, Death and Regeneration on February 22-27, 2011 in Keystone, Colorado. The award is made possible through the National Heart, Lung, and Blood Institute.
Clinical Science
Latest from the Center of Excellence on Returning War Veterans
The Center of Excellence on Returning War Veterans hosted Sonja Batten, Ph.D. the Assistant Deputy Chief PCS Officer for Mental Health, VACO on January 10th and 11th , 2011 for training in Acceptance and Commitment Therapy for co-occurring PTSD and Substance use Disorders. The training was provided to 16 clinical psychologists-including both CoE clinical researchers and CTVHCS staff clinicians from Waco, Temple and Austin, TX.
John Klocek, Ph.D. will be providing training in COPE (Concurrent Treatment with Prolonged Exposure) and evidence-based therapy for co-occurring PTSD and substance dependence [Brady T, Dansky BS, Back SE, Foa, EB and Carroll, KM (2001). Exposure therapy in the treatment of PTSD among cocaine-dependent: preliminary findings. Journal of Substance Abuse Treatment 21, 47-54]. Training dates are January 27th and 28th, 2011, from 8:30 AM to 4:00 PM at the Center of Excellence on Returning War Veterans Boardroom in Waco, TX. Attendees will include health care professionals from Waco, Temple, Austin, San Antonio and members of the CoE.
*Names in bold are CoE staff
Publications
Kareken DA, Bragular V, Dzemdzic M, Cox C, Talavage T, Davidson D, O’Connor SJ (2010).
Family History of alcoholism mediates the frontal response to alcohol drink odors and alcohol in at-risk drinkers. Neuroimage, 50, 267-276.
Gartner A, Dolan S, Elkins G, Stanford M (in press) Hypnosis in the treatment of Morgellons Disease: a case study. Int J Clin & Exp Hypnosis
Gulliver SB, Klocek, J, Steffen LE (2010). Stanley falls flat at the IRB. The Behavior Therapist.
Gulliver SB, Steffen LE (2010). Towards integrated treatments for PTSD/SUD. PTSD Research Quarterly, V21.
Nelson-Gray RO, Lootens CM, Mitchell JT, Hundt NE, Robertson CD, Kimbrel NA (2010). Assessment and treatment of personality disorders: A behavioral perspective. The Behavior Analyst Today 10 13-15.
Hundt NE, Mitchell JT, Kimbrel NA, Nelson-Gray RO (in press). The effect of behavioral inhibition and behavioral approach on social functioning. Individual Differences Research.
Kimbrel NA, Mitchell JT, Nelson-Gray RO (2010). An examination of the relationship between behavioral approach system (BAS) sensitivity and social interaction anxiety. Journal of Anxiety Disorder 24, 372-378.
Kimbrel NA, Mitchell JT, Hundt NE, Robertson CD, Nelson-Gray RO (in press). BIS and BAS interact with perceived parental affectionless control to predict personality disorder symptomatology. Journal of Personality Disorders
Kruse MI, Steffen LE, Kimbrel NA, Gulliver SB (in press). Co-Occurring PTSD and Substance Use Disorders. Psychosocial treatment of co-morbid Post-Traumatic Stress Disorder and Substance Use Disorders. Handbook for the treatment of PTSD in Military Personnel
Meyer EC, Lynn SJ (in press). The determinants of hypnotic and nonhypnotic suggestibility. The International J of Clinical and Experimental Hypnosis
Kruse MI, Steffen LE, Kimbrel NA, Gulliver SB (in press). Co-Occurring PTSD and Substance Use Disorders. Psychosocial treatment of co-morbid Post-Traumatic Stress Disorder and Substance Use Disorders. Handbook for the treatment of PTSD in Military Personnel
Glahn DC, Robinson JL, Tordesillas-Gutierrez D, Monkul ES, Holmes MK, Fox PT, Green MJ, Bearden CE (in press). Fronto-temporal dysregulation in asymptomatic bipolar I patients: A paired associate functional MRI study. Human Brain Mapping.
Laird AR. Robinson JL, McMillan KM, Tordesillas-Gutierrez D, Moran ST, Gonzales SM, Ray KL, Franklin C, Glahn DC, Fox PT, Lancaster JL. (in press). Comparison of the disparity between Talairach and MNI coordinates in functional neuroimaging data: Validation of the Lancaster transform. Neuroimage
Tsan JY, Day SX, Schwartz JP, & Kimbrel NA (in press) Restrictive Emotionality, BIS, BAS, and Psychological Help-Seeking Behavior Psychology of Men and Masculinity.
Posters
Kruse MI (2010). PTSD in Healthcare Settings Serving Military Veterans. CTVHCS Medical Grand Rounds. Temple, TX
Marino-Carper T, Lawrence AE, Arditte KA, Kamholz BW, Liverant GI, Gulliver SB (2010). Phenomenology of psychiatric ever-smokers: diagnostic differences between successful quitters and current smokers phenomenology of psychiatric ever-smokers: diagnostic differences between successful quitters and current smokers. San Francisco, CA
Meyer EC, Evans Y, Fay CL, Chrestman R, Kimbrel NA, Kruse MI, Gulliver SB, Morissette SB (2010). Experiential avoidance, personality, cognitive functioning and social support as a predictors of psychology among Operation Enduring Freedom and Operational Iraqi Freedom (OEF/OIF) veterans. 24th Annual meeting of the Society for Research Psychopathology. Seattle, WA
Meyer EC, Evans Y, Fay CL, Chrestman R, Kimbrel NA, Kruse MI, Gulliver SB, Morissette SB (2010). Experiential avoidance as a predictor of functional outcomes among Operation Enduring Freedom and Operational Iraqi Freedom (OEF/OIF) veterans. Experiential avoidance as a predictor of functional outcomes among Operation Enduring Freedom and Operational Iraqi Freedom (OEF/OIF) veterans. Seattle, WA
Meyer EC, Zimering R, Daly E, Kamholz BW, Knight J & Gulliver SB (2010). Predictors of mental health and occupational outcomes among experienced professional firefighters. International Society for Traumatic Stress Studies. Montreal, QC
Morissette SB (2010). Examining the Relationship between TBI-Related Post-Concussive Symptoms and Combat Exposure on PTSD, Depression, and Sleep Quality. Texas A&M Health Science Center Research Symposium College Station, TX
Robinson J (2010). Meta-analytic connectivity modeling: developing robust models of functional connectivity using functional neuroimaging data. TAMU Neuroscience Seminar. College Station, TX
Robinson J (2010). Neuroimaging for the Neurosciences. TAMIN Seminar Series. College Station, TX
Seidman LJ, Woodberry K, Giuliano AJ, Meyer EC, Addington J, Cadenhead KS, Cannon TD, McGlashan TH, Perkins DO, Tsuang MT, Walker EF, Woods SW, Heinssen R & Cornblatt BA (2010). Method and results from an individual classification approach to neuropsychological data in clinical high risk individuals in the NAPLS Consortium. 7th International Early Psychosis Association Conference, Amsterdam, Netherland
Steffen LE, Mardikar AA, Kruse MI, Kamhoz BW & Zimering RT (2010). Aggression as a predictor of heavy drinking during the first year of fire service. International Society for Traumatic Stress Studies. Montreal, QC
Steffen LE, Mardikar AA, Kruse MI, Kimbrel NA, Zimering RT & Gulliver SB (2010). Multi-method approach to studying behavioral health implementation in fire service. 118th Annual Scientific Meeting of the American Psychological Association. San Diego, CA
Tsan J (2010). Careers in Psychology at the Veterans Affairs Hospital. Baylor University Psy Chi
Tsan JY, Greenawalt DS, Kimbrel N, Meyer E, Tharp D, Gulliver SB, Morissette SB Minority Treatment Involvement for Depression and PTSD Among Returning OEF/OIF Veterans. Texas A&M Health Science Center Research Symposium, College Station, TX
Tsan JY, Greenawalt DS, Kimbrel NA, Meyer EC, Tharp D, Gulliver SB, Morissette SB (2010). Minority status moderates involvement in individual psychotherapy for depression among returning OEF/OIF Veterans. Texas A&M Health Science Center Research Symposium. College Station, TX
Young KA, Harrington GS, Robinson JL, Jamroz RC, Wan JL, Griffin JL, Hicks PB (2010). Thalamocortical sheer: probabilistic tracking for quantification of structure connectivity in TBI. 2010 Society for Neuroscience San Diego, CA
Young KA, Harrington GS, Standford, MS, Jamroz R, Wan L, Kressin RM, Miller LJ, Keele, (2010) Society for Neuroscience NB, Hicks PB (2010). Childhood trauma & thalamic enlargement: suspended maturation of the thalamocortical system associated with enhanced levels of neurotrophins. 2010 Society for Neuroscience San Diego, CA
INTERNAL MEDICINE
In order to generate an accurate count of scholarly products within the Department of Medicine, all scholarly products are counted only once and are not reported for every faculty member involved. For the purposes of this departmental report, a scholarly product will be counted under the first author’s division or program only. If the first author is not in the Department of Internal Medicine, credit will be assigned to the highest author in IM.
Total Numbers
5 Peer-reviewed publications
10 Manuscripts accepted/in review/in press
19 Abstracts accepted/presented
0 Book chapters
7 Research projects
13 Presentations
13 Posters/exhibits
19 Lectures
2 Articles reviewed
0 Grants received
6 Notable accomplishments
3 Educational Projects
Reported by Division
Gastroenterology – Lab
3 Publications
15 Abstracts
1 Presentations
4 Research Projects
1 Lectures
1 Articles Reviewed
1 Notable Accomplishments
General Internal Medicine
1 Lecture
1 Publications
Hematology/Oncology
1 Publication
Hospital Medicine
7 Lectures
Nephrology
2 Abstracts
3 Posters/exhibits
9 Lectures
Nephrology Lab
1 Presentations
5 Manuscripts
1 Articles Reviewed
2 Notable Accomplishments
Pulmonary Disease
7 Presentations – See also Medical Education (UME/GME)
Abstracts – See Medical Education (UME/GME)
3 Research Projects
4 Posters/exhibits – See also Medical Education (UME/GME)
1 Lectures
3 Educational Projects
Reported by Program
Medical Education(UME/GME)
4 Manuscripts
2 Abstracts
5 Posters/exhibits
4 Presentations
3 Notable Accomplishments
Collaborative Research
1 Manuscripts- In review
1 Posters/exhibits
Publications – Peer-Reviewed
General Internal Medicine
1. Elijovich F, Laffer CL: Acute stroke: lower blood pressure looks better and better. Hypertension 56:808-810,2010 (November issue)
Gastroenterology Lab-
1. Adenosine triphosphate release and purinergic (P2) receptor-mediated secretion in small and large mouse cholangiocytes. Woo K, Sathe M, Kresge C, Esser V, Ueno Y, Venter J, Glaser SS, Alpini G, Feranchak AP. Hepatology. 2010. Nov;52(5):1819-28.
2. Identification and functional characterization of TMEM16A, a Ca2+-activated Cl- channel activated by extracellular nucleotides, in biliary epithelium. Dutta AK, Khimji AK, Kresge C, Bugde A, Dougherty M, Esser V, Ueno Y, Glaser SS, Alpini G, Rockey DC, Feranchak AP. J Biol Chem. 2010 Nov 1. PMID: 21041307
3. A K Dutta, Al-k Khimji, C Kresge, A Bugde, M Dougherty, Vi Esser, Y Ueno, S Glaser, G Alpini, D C Rockey, and A P Feranchk. Identification and functional characterization of TMEM16A, a Ca2+-activated Cl- channel activated by extracellular nucleotides, in biliary epithelium. JBC, in press, J Biol Chem. 2010 Nov 1. [Epub ahead of print], PMID: 21041307 [PubMed - as supplied by publisher].
Hematology/Oncology
1. Woo JH, Frankel A, Neville DM. Cytotoxic Therapy with Diptheria toxin fusion proteins. Drugs of the Future. 2010, 35(10):823-831.
Manuscripts – In review/Accepted/In press
Medical Education(UME/GME)
Residency Program & OMEERD
1. McNeal T, Colbert CY, Cable C, Mirkes C, Lubowinski J, Myers JD. Patient’s attention to and understanding of adverse drug reaction warnings. Patient Intelligence. Invited review. In press Nov 2010.
OMEERD
2. Colbert CY, Ogden PE, Ownby AR, Bowe C. Systems-Based Practice in Graduate Medical Education: Systems Thinking as a Foundational Construct. Teaching and Learning in Medicine. In press Nov 2010.
UME
3. Cable CT, Ahluwalia R, Mirkes C, Colbert CY. A case of disseminated intravascular coagulation associated with a prosthetic heart valve. Amer J of Med Sci. In press Nov 2010. Rohan Ahluwalia, MD was a 4th-year medical student at the time.
4. Cable CT, Colbert CY, Showalter T, Ahluwalia R, Song J, Whitfield P, Rodriquez J. Prevalence of anemia after Roux-en-Y gastric bypass surgery: What’s the right number? Surgery for Obesity and Related Diseases. In press Nov 2010. Rohan Ahluwalia, MD was a 4th-year medical student at the time.
Collaborative Research
1. Wehbe-Janek H, Song J, Shabahang M. An Evaluation of the Usefulness of the Standardized Patient Methodology in the Assessment of Surgery Residents' Communication Skills. Journal of Surgical Education. Accepted, J Surgical Education
Nephrology Lab
1. Chatterjee P, Weaver LE, Chiasson VL, Young KJ, Mitchell BM. Do double-stranded RNA receptors play a role in preeclampsia? Placenta 2010;(in 2nd review).
2. Chiasson VL, Munshi N, Young KJ, Mitchell BM. Pin1 deficiency increases endothelial nitric oxide synthase serine 116 phosphorylation, endothelial dysfunction, and blood pressure. Circ Res 2010;(in review). Chiasson VL, Quinn MA, Young KJ, Mitchell BM. PKCbetaII-mediated phosphorylation of eNOS threonine 495 mediates the endothelial dysfunction induced by tacrolimus. J Pharmacol Exp Ther 2010;(in review).
3. Chiasson VL, Talreja D, Young KJ, Chatterjee P, Banes-Berceli A, Mitchell BM. FK506 binding protein 12 deficiency in endothelial and hematopoietic cells decreases regulatory T cells and causes Th17 cell-mediated hypertension. Hypertension 2010;(in 2nd review).
4. Chiasson VL, Jones KA, Mahajan A, Young KJ, Mitchell BM. Endothelial FK506 binding protein 12 deficiency causes renal arteriole hyalinosis. J Am Soc Nephrol 2010;(in review).
5. Chatterjee P, Chiasson VL, Young KJ, Chatterjee V, Mitchell BM. Interleukin-10 deficiency exacerbates Toll-like receptor 3-induced preeclampsia-like symptoms in mice. Hypertension 2010;(in 3rd review).
Abstracts – Accepted/Presented
Medical Education (UME/GME)
Internal Medicine Residency Program
1. VJ Scott, MH Henderson, CD Spradley. Extranodal Rosai-Dorfman Disease Presenting as Hemoptysis: A Case Report. Chest. 2010; 138(4):119A
Pulmonary Fellowship & IM Residency Program
2. MH Henderson, VJ Scott, BC Barnett, CD Spradley. Pulmonary Hypertension Registry: A Local Experience Compared to National Baseline Characteristics. Chest. 2010; 138(4):371A
Gastroenterology Lab
1. H Francis, J Venter, T Francis, P Onori, S Kopriva, S DeMorrow, W Butler, M White, A Franchitto, F Meng, E Gaudio, and G Alpini. While Ca2+-dependent small cholangiocyte proliferation is mediated by the activation of H1 histamine receptors (H1HR), cAMP-dependent large cholangiocyte growth depends on the activation of H2HR. Poster presentation at American Association for the Studies of Liver Diseases, Boston, 2010, Hepatology 52: A1238 (233A), 2010.
2. S Glaser, P Onori, j Venter, M White, S Kopriva, Y Ueno, F Meng, A Franchitto, E Gaudio, R Mancinelli, and G Alpini. Neurogenic differentiation 1 (NeuroD1) is required for the de novo expression of secretin and the neuroendocrine differentiation of small cholangiocytes during the damage of large cholangiocytes. Poster presentation at American Association for the Studies of Liver Diseases, Boston, 2010, Hepatology 52: A1245 (234A), 2010.
3. A Renzi, P Onori, S DeMorrow, Y Han, R Mancinelli, S Glaser, H Francis, J Venter, S Kopriva, A Franchitto, W Butler, M White, Y Ueno, F Meng, E Gaudio, and G Alpini. Increased expression of serotonin N-acetyltransferase (AANAT, the key enzyme responsible for the synthesis of melatonin) in cholangiocytes causes inhibition of biliary proliferation: evidence for a novel autocrine loop regulating biliary hyperplasia. Poster presentation at American Association for the Studies of Liver Diseases, Boston, 2010, Hepatology 52: A1243 (234A), 2010.
4. A Holterman, K Wang, S Glaser, Y Uneo, H Chen, and G Alpini. Differential transcriptional characteristics of small and large biliary epithelial cells derived from small and large bile ducts. Poster presentation at American Association for the Studies of Liver Diseases, Boston, 2010, Hepatology 52: A1247 (234A), 2010.
5. L L Hubble, H Francis, S DeMorrow, Y Han, S Glaser, J Venter, Li Huang, S Kopriva, Y Ueno, S Priester, G Alpini, and F Meng. TGF-β mediated colony-stimulating factors regulation of cholangiocyte remodeling during hepatic regeneration. Poster presentation at American Association for the Studies of Liver Diseases, Boston, 2010, Hepatology 52: A1244 (234A), 2010.
6. F Meng, S Glaser, H Francis, S DeMorrow, T Lairmore, L Wong, M W Majdoub, J D Passarini, Jay Sharma, Y Han, Md. K Munshi, L L Hubble, J Ramirez, S Priester, and G Alpini. Epigenetic regulation of CD133 and chemosensitivity in human gallbladder cancer stem cells. Oral presentation at American Association for the Studies of Liver Diseases, Boston, 2010, Hepatology 52: A245 (93A), 2010.
7. A Omenetti, LL Bass, R Anders, MG Clemente, H Francis, CD Guy, SS Choi, G Alpini, K Schwarz, P Whitington, and AM Diehl. Hedgehog pathway drives the acquisition of mesenchymal markers in ductular cells of patients with biliary atresia. Oral presentation at American Association for the Studies of Liver Diseases, Boston, 2010, Hepatology 52: A1462 (256A), 2010.
8. Y Han, Q Jing, H Francis, S Glaser, A Stokes, S Priester, L L Hubble, C-G Liu, J Venter, G Alpini, H Tsukamoto, and F Meng. Emerging roles of microRNAs in the control of apoptosis and transformation in hepatobiliary cells during alcoholic liver injury. Oral presentation at American Association for the Studies of Liver Diseases, Boston, 2010, Hepatology 52: A121 (93A), 2010.
9. EMERGING ROLES OF MICRORNAS IN THE CONTROL OF APOPTOSIS AND TRANSFORMATION IN HEPATOBILIARY CELLS DURING ALCOHOLIC LIVER INJURY
Yuyan Han, Qing Jing, Heather Francis, Shannon S. Glaser, Allison Stokes, Sally Priester, Levi L. Hubble, Chang-Gong Liu, Julie Venter, Gianfranco Alpini, Hidekazu Tsukamoto, Fanyin Meng Hepatology, Volume 52, Issue Supplement S1, A121, pg 379A, 2010
10. CHOLANGIOCYTES EXPRESS 17β-HYDROXYSTEROID DEHYDROGENASE TYPE 3 (17β-HSD3) AND SECRETE TESTOSTERONE PROMOTING CHOLANGIOCYTE PROLIFERATION IN AN AUTOCRINE MECHANISM DURING CHOLESTASIS INDUCED BY BILE DUCT LIGATION (BDL)
Sally Priester, Fuquan Yang, Julie Venter, Candace Wise, Md. Kamruzzaman Munshi, Sarah Keyser, Micheleine Guerrier, Marco Marzioni, Yoshiyuki Ueno, Shannon S. Glaser Hepatology, Volume 52, Issue Supplement S1, A219, pg 432A, 2010
11. EPIGENETIC REGULATION OF CD133 AND CHEMOSENSITIVITY IN HUMAN GALLBLADDER CANCER STEM CELLS
Fanyin Meng, Shannon S. Glaser, Heather Francis, Sharon DeMorrow, Terry Lairmore, Lucas Wong, Mariam W. Majdoub, Jenna D. Passarini, Jay Sharma, Yuyan Han, Md. Kamruzzaman Munshi, Levi L. Hubble, Jonathan Ramirez, Sally Priester, Gianfranco Alpini Hepatology, Volume 52, Issue Supplement S1, A245, pg 445A, 2010
12. INCREASED EXPRESSION OF SEROTONIN N-ACETYLTRANSFERASE (AANAT, THE KEY ENZYME RESPONSIBLE FOR THE SYNTHESIS OF MELATONIN) IN CHOLANGIOCYTES CAUSES INHIBITION OF BILIARY PROLIFERATION: EVIDENCE FOR A NOVEL AUTOCRINE LOOP REGULATING BILIARY HYPERPLASIA
Anastasia Renzi, Paolo Onori, Sharon DeMorrow, Yuyan Han, Romina Mancinelli, Shannon S. Glaser, Heather Francis, Julie Venter, Shelley Kopriva, Antonio Franchitto, Wendy Butler, Mellanie White, Yoshiyuki Ueno, Fanyin Meng, Eugenio Gaudio, Gianfranco Alpini Hepatology, Volume 52, Issue Supplement S1, A1243, pg 924A, 2010
13. TGF-β MEDIATED COLONY-STIMULATING FACTORS REGULATION OF CHOLANGIOCYTE REMODELING DURING HEPATIC REGENERATION
Levi L. Hubble, Heather Francis, Sharon DeMorrow, Yuyan Han, Shannon S. Glaser, Julie Venter, Li Huang, Shelley Kopriva, Yoshiyuki Ueno, Sally Priester, Gianfranco Alpini, Fanyin Meng Hepatology, Volume 52, Issue Supplement S1, A1244, pg 924A, 2010
14. NEUROGENIC DIFFERENTIATION 1 (NEUROD1) IS REQUIRED FOR THE DE NOVO EXPRESSION OF SECRETIN AND THE NEUROENDOCRINE DIFFERENTIATION OF SMALL CHOLANGIOCYTES DURING THE DAMAGE OF LARGE CHOLANGIOCYTES
Shannon S. Glaser, Paolo Onori, Julie Venter, Sharon DeMorrow, Mellanie White, Shelley Kopriva, Yoshiyuki Ueno, Fanyin Meng, Antonio Franchitto, Eugenio Gaudio, Romina Mancinelli, Gianfranco Alpini Hepatology, Volume 52, Issue Supplement S1, A1245, pg 925A, 2010
15. DIFFERENTIAL TRANSCRIPTIONAL CHARACTERISTICS OF SMALL AND LARGE BILIARY EPITHELIAL CELLS DERIVED FROM SMALL AND LARGE BILE DUCTS
Aixuan Holterman, Kewei Wang, Shannon S. Glaser, Yoshiyuki Ueno, Huiqing Chen, Gianfranco Alpini Hepatology, Volume 52, Issue Supplement S1, A1247, pg 926A, 2010
Nephrology
1. Prediction of Cardiovascular Disease during Pre-Transplant Evaluation: Nimrit Goraya, Mohanram Narayanan, Luis Concepcion. J Am Soc Nephrol 21:2010; 329A
2. Enteric-Coated Mycophenolate Sodium (EC-MPS) Versus Mycophenolate Mofetil (MMF) in African American (AA) Renal Transplant Recipients from the Mycophenolic Acid Observational Renal Transplant (MORE) Registry: Mohanram Narayanan, Oleh Pankewycz, et al. J Am Soc Nephrol 21:2010; 325A.
Presentations
Gastroenterology Lab
1. NEUROGENIC DIFFERENTIATION 1 (NEUROD1) IS REQUIRED FOR THE DE NOVO EXPRESSION OF SECRETIN AND THE NEUROENDOCRINE DIFFERENTIATION OF SMALL CHOLANGIOCYTES DURING THE DAMAGE OF LARGE CHOLANGIOCYTES
Shannon S. Glaser, Paolo Onori, Julie Venter, Sharon DeMorrow, Mellanie White, Shelley Kopriva, Yoshiyuki Ueno, Fanyin Meng, Antonio Franchitto, Eugenio Gaudio, Romina Mancinelli, Gianfranco Alpini Hepatology, Volume 52, Issue Supplement S1, A1245, pg 925A, 2010 National. American Association for the Study of Liver Disease Annual Meeting, November 2010.
Medical Education (UME/GME)
IM Residency Program – Resident
1. Brian C. Barnett, MD – Incidence of Legionella Pneumonia as Diagnosed by Urinary Legionella Antigen Testing: A Retrospective Analysis – Chest 2010, November 2, 2010, 4:30 – 6:00 pm
2. Vincent J. Scott, M.D. – Extranodal Rosai-Dorfman Disease Presenting as Hemoptysis: A Case Report – Chest 2010, November 3, 2010, 10:30 – 12:00 pm
IM Residency Program & Pulmonary Fellowship
3. VJ Scott, MH Henderson, CD Spradley. Extranodal Rosai-Dorfman Disease Presenting as Hemoptysis: A Case Report. Chest. 2010; 138(4):119A CHEST Vancouver, BC
Pulmonary Fellowship
4. Heather Henderson, M.D. IgA Capillaritis Causing Diffuse Alveolar Hemorrhage in a Renal Transplant A Patient: A Case Report and Review of the Literature. Chest 2010, November 1, 2010 10:30 to 12 pm
Nephrology Lab
1. Mitchell BM. Role of dsRNA Receptors in Preeclampsia. Texas A&M Health Science Center/S&W Dept. of OB/GYN, Temple, TX, November 15, 2010.
Pulmonary
1. James Barker, M.D., FCCP, Restless Legs Syndrome and Periodic Limb Movements of Sleep, Chest 2010, October 30, 2010, 3:00 – 3:50 pm
2. James A. Barker, M.D., FCCP, Moderator, Surgical Surprises, Monday, November 1, 2010, 10:30 – 12:00 pm
3. James Barker, M.D. “Are You Smarter Than a PGY-5? Sleep Medicine Edition” - Adult Sleep Disorders, Chest 2010, November 2, 2010, 8-9:15 am
4. James A. Barker, M.D., FCCP, Moderator, Sepsis and Shock, Monday, November 3, 2010, 8:00 – 9:15 am
5. William G. Petersen, M.D. Comparison of Pleural Fluid pH Using Two Methods of Pleural Fluid Collection: Blood Gas Syringe vs Lithium-Heparin Vacuette (Green-Topped Tub GTT) Chest 2010, November 2, 8-9:15 am
6. Rupesh Dave, M.D. – An Unusual Case of Metastatic Synovial Sarcoma Presenting With a Pneumothorax – Chest 2010, November 2, 2, 2010 1O:30 am – 12:00 pm
7. Benjamin Culp, M.D. – The Pocket Echocardiograph: A Pilot Study of Its Validation and Feasibility in Intubated Patients, Chest 201, November 2, 8: - 9:15 am
Posters/Exhibits
Medical Education (UME/GME)
1. Internal Medicine Residency Program
Boucher M, Beckendorf R. “All that Wheezes is Not Asthma: A Case of Bronchial Carcinoid.” Poster presented at the Texas Chapter of the ACP meeting, Houston, TX, Nov. 2010. See notable accomplishments. Dr. Boucher is a PGY-3 resident in the Internal Medicine Residency Training Program.
2. Internal Medicine Residency Program
Samuel L, Myers J. “Coitus Interruptus: A Case of Reflex Seizure.” Poster presented at the Texas Chapter of the ACP meeting, Houston, TX, Nov. 2010. Dr. Samuel is a PGY-1 resident in the Internal Medicine Residency Training Program.
3. Pulmonary Fellowship Program & IM Residency Program
MH Henderson, VJ Scott, BC Barnett, CD Spradley. Pulmonary Hypertension Registry: A Local Experience Compared to National Baseline Characteristics. Chest. 2010; 138(4):371ACHEST Vancouver, BC
4. Pulmonary Fellowship Program
Diana Guerra, M.D. Examining Readmissions in ICU Patients: An Observational Study After Hospital Discharge, Chest 2010, November 2, 2010, November 2, 2010, 12:45 – 2:00 pm
5. Pulmonary Fellowship Program
Heather Henderson, M.D. Pulmonary Hypertension Registry: A Local Experience Compared to National Baseline Characteristics, Chest 2010, November 2, 2010, 12:45 – 2:00 pm
Collaborative Research
1. C Govednik-Horny, H Wehbe-Janek, C Colbert, B White, M Shabahang. A qualitative assessment of residents’ perspectives of the value of simulation in a General Surgery Residency curriculum. 121st Annual Meeting of the American Association of Medical Colleges,49th Annual Conference on Research in Medical Education (RIME), 2010, Presented Nov 5-10, 2010 in Washington, DC
Nephrology
1. Can we predict cardiovascular disease based on echocardiographic and demographic variables in our transplant clinic?: Nimrit Goraya, Mohanram Narayanan, Luis Concepcion. Poster presentation at the American Society of Nephrology’s 43rd Annual Meeting & Scientific Exposition, November 18-21, 2010, Denver CO.
2. Adding Dietary Fruits & Vegetables Reduces Kidney Injury in Subjects with Moderately Reduced GFR: Nimrit Goraya, Donald Wesson, et al. Poster presentation at the American Society of Nephrology’s 43rd Annual Meeting & Scientific Exposition, November 18-21, 2010, Denver CO.
3. Enteric-Coated Mycophenolate Sodium (EC-MPS) Versus Mycophenolate Mofetil (MMF) in African American (AA) Renal Transplant Recipients from the Mycophenolic Acid Observational Renal Transplant (MORE) Registry: Mohanram Narayanan, Oleh Penkewycz et al. Poster presentation at The American Society of Nephrology 43rd Annual Meeting & Scientific Exposition, November 18-21, 2010. Denver CO.
Pulmonary Division
1. Benjamin Culp, M.D. – Noninvasive Assessment of Central Venous Pressure by Miniaturized Echocadiography – Chest 2010, November 2, 2010 – 12:45 – 2:00 pm
2. Francisco Javier Flores Guardado, M.D. (presented by Alejandro Arroliga, M.D.) Etiologies and Outcomes of Hemoptysis in the Intensive Care Unit, Chest 2010, November 2, 2010, 12:45 – 2:00 pm
3. Pedro Quiroga, M.D. Utilization of an Abbreviated Methacholine Challenge Protocol for Detection of Airway Hyperreactivity, Chest 2010, November 2, 2010, 12:45 – 2:00 pm
4. Rupesh Dave, M.D., Jorge Velazco, M.D. - Outcomes Study: 8 Year Experience of Patients with Isolated Reduction in Diffusion Capacity (DLCO), Chest 2010, November 3, 12:45 pm to 2:00 pm
Lectures
General Internal Medicine
1. Laffer C- Department of Medicine, Texas A&M Health Science Center College of Medicine 3rd Year Clerkship Lecture: “Hypertensive urgencies”
Hospital Medicine
1. Varghees S – Seizures, MS3 inpatient lecture series, Nov. 1, 2010
2. Rajan – Ethics, MS3 inpatient lecture series, Nov.2, 2010
3. Laffer – HTN Urgencies, MS3 inpatient lecture series, Nov. 8, 2010
4. Rajan – Pain Management, MS3 inpatient lecture series, Nov.9, 2010
5. Win – Acid Base-Optional, MS3 inpatient lecture series, Nov.11, 2010
6. Reddy S – Anemia, MS3 inpatient lecture series, Nov.15, 2010
7. Deppisch – EGK Review MS3 inpatient lecture series, Nov.22, 2010
Nephrology
1. Enoch Agunanne, MD: “Kidney Transplantation”, Nephrology Journal Club, November 24, 2010. Scott & White Temple. (fellows, senior staff)
2. Concepcion LA- Nephritic Syndrome: Internal Medicine Residents Noon Conference, November 4, 2010. Scott & White Temple. (residents)
3. Concepcion LA- Biostatistics Seminar, Part II: November 10, 2010. Scott & White Temple. (fellows & senior staff)
4. Concepcion LA- Peritoneal Dialysis, Complication Management: Nephrology Core Lecture, November 17, 2010. Scott & White Temple. (fellows & senior staff)
5. Concepcion LA- Biostatistics Seminar, Part III: November 24, 2010. Scott & White Temple (fellows & senior staff)
6. Hoang-Lan Nguyen, DO: “Mechanisms of Urinary Concentration and Dilution, Counter Current Mechanism”, Basic Science-Renal Physiology Conference, November 11, 2010. Scott & White Temple. (fellows, senior staff)
7. Geetha Seerangan: “Uremic Pericarditis”. Nephrology Morbidity & Mortality Conference, November 3, 2010. (fellows & senior staff).
8. Geetha Seerangan: “Renal Vasculitis Treatment”. Nephrology Journal Club, November 10, 2010. (fellows & senior staff)
9. Mohanram Narayanan: Internal Medicine Residents Noon Conference: “Urinalysis”, November 2, 2010. Scott & White Temple (residents)
Gastroenterology Lab
1. Glaser-Stomach Physiology: Basic Functions and Control
Medical Students: Phase II GI Block Thursday, November 11, 2010 (2 hrs)
Pulmonary
1. Spradley- “Scleroderma and the Lung” Scleroderma Support Group - Waco
Articles Reviewed – Peer-Reviewed Journals – Nov. 2010
Gastroenterology Lab
1. Glaser-Digestive and Liver Disease
Biomarkers of Cancer
Hepatology Archives of Medical Research
Nephrology Lab – Articles Reviewed
1. Mitchell BM– 6 – Hypertension
Notable Accomplishments: Faculty News, Appointments, Nominations
Gastroenterology Lab
1. G Alpini Co-moderator of a session at AASLD meeting “Alcohol: Clinical and Experimental”, November 1, 2010, at American Association for the Studies of Liver Diseases Meeting.
Medical Education(UME/GME)
1. Scott & White/Texas A&M HSC COM Internal Medicine Residency Program
The Internal Medicine Residency Program’s Jeopardy Team (Jonathan Ramirez, MD, Shannon Ward, MD and Scott Swendson, MD) won 1st Place in the Doctor’s Dilemma Competition, a medical jeopardy game competition, at Texas ACP, Houston, TX, Nov. 12, 2 010. Each of the three residents received a cash prize and will represent Texas ACP at the National Competition in San Diego, CA in April 2011.
2. Texas A&M HSC COM student
Condit R. - “Rheum for Debate.” Rebekah Condit, MS3, won first place in the Oral Clinical Vignette Competition at the Texas Chapter of the American College of Physicians (ACP), Nov. 2010, Houston, TX.
3. Scott & White/ Texas A&M HSC COM Internal Medicine Residency Program
Boucher M, Beckendorf R. “All that Wheezes is Not Asthma: A Case of Bronchial Carcinoid.” Presented at the Texas Chapter of the ACP meeting, Houston, TX, Nov. 2010. Dr. Miranda Boucher, a PGY-3 resident, won 1st place in the Associates poster competition at Texas ACP.
Nephrology Lab
1. Mitchell BM– Appointed to Editorial Board for American Journal of Physiology-Heart and Circulatory Physiology
2. Mitchell BM– Appointed to Editorial Board for Frontiers in Pharmacotherapy of Cardiovascular Disorders
Research Projects
Gastroenterology Lab
1. Autocrine/Paracrine Regulation of Intrahepatic Bile Duct Growth. VA Merit Award
2. Regulation of bile duct growth in bile duct ligated rats. NIH
3. Growth Regulation of the Intrahepatic Biliary Tree. NIH
4. Role of Sensory Neuropeptides in the Regulation of Biliary Function
Pulmonary
1. Site Initiation: AMBITION (Combination RX in PAH)
2. Ongoing: PH Registry (Henderson, Barnett, Scott)
3. Ongoing: ICU Videos (Henderson, Barnett, Scott)
Educational Projects
Pulmonary
1. Planning Stages: MICU Resident Rotation Curriculum
2. Planning Stages: Combined ED/MICU/Hospitalist MS IV
3. Rotation (Linear model: Follow the patient, not the service)
INTERNAL MEDICINE RESEARCH
Dr. Alpini
Attend a VA study session, Gastroenterology, December 2010.
Activation of alpha(1)-adrenergic receptors stimulate the growth of small mouse cholangiocytes Via calcium-dependent activation of nuclear factor of activated T cells 2 and specificity protein 1.Alpini G, Franchitto A, Demorrow S, Onori P, Gaudio E, Wise C, Francis H, Venter J, Kopriva S, Mancinelli R, Carpino G, Stagnitti F, Ueno Y, Han Y, Meng F, Glaser S. Hepatology. 2010 Oct 18. [Epub ahead of print]PMID: 21204075 [PubMed - as supplied by publisher]
Heather Francis
Graduated December 17th from TAMU HSC - PhD Medical Sciences Accepted a position in the DDRC at S&W as a Research Scientist/Assistant Professor
Academic Medicine
Cardiovascular Research Institute
Division of Molecular Cardiology
Presentations
Kenneth M. Baker
Dr. Baker presented the talk entitled “Intracellular Renin-Angiotensin System: A New Paradigm. Implications for Diabetic Cardiomyopathy” at the Texas A&M Health Science Center Research Symposium, November 11-12, 2010 in College Station, Texas.
David E. Dostal
Dr. Dostal was an invited speaker for the Preclinical Micro-Ultrasound Imaging Workshop sponsored by Visualsonics at Texas Children’s Hospital, at Houston, Texas on Oct. 27, 2010. The title of his presentation was “Measuring Developmental Changes in Cardiac Function in the Mouse Fetus.”
Dr. Dostal was an invited speaker for the Department of Cell and Molecular Physiology Seminar Series at Loyola University, Chicago, IL on Nov. 17, 2010. The title of his presentation was “Unraveling the Signaling Pathways Associated with Anthrax Lethal Toxin-Induced Heart Failure”.
Professional Service
David E. Dostal
Dr. Dostal has been appointed as the new IACUC Chair for the Scott & White and Texas A&M IACUC on the Temple Campus.
Dr. Dostal participated in the Department of Veterans Affairs Cardiovascular Studies A (CARA) Merit Review Subcommittee in Washington DC on Nov 3, 2010.
Dr. Dostal participated as a panel member for the NIH Cardiac Contractility, Hypertrophy and Failure Study Section in Washington DC on October 13-14, 2010.
Dr. Dostal served as a teleconference reviewer for the American Heart Association Molecular Signaling 3 Peer Review Study Group on October 22, 2011.
Abstracts/Posters (presented)
Honey Golden
AHA Scientific Sessions 2010, Chicago, IL. “Unraveling the Phospholamban Signaling Network in Anthrax Lethal Toxin-Induced Cardiac Dysfunction”, poster, Best of AHA Specialty Conferences Poster Session: BCVS 2010.
Grants/Awards
Rakeshwar S. Guleria
Dr. Guleria received a Scott & White Research Grants Program (SWRGP) award entitled “Retinoid Receptors in Diabetes-Induced Cardiac Remodeling”. Co-PI’s are Drs. Kenneth M. Baker and Jing Pan
David E. Dostal
Dr. Dostal received a Scott & White Research Grants Program (SWRGP) award entitled “Cardiac Effects of Anthrax Lethal Toxin: Unraveling the Mechanisms for Sodium and Calcium Dysregulation”.
Publications
Guleria RS, Choudhary R, Tanaka T, Baker K, Pan J. 2010. Retinoic Acid Receptor-Mediated Signaling Protects Cardiomyoctes from Hyperglycemia Induced Apoptosis: Role of the Renin-Angiotensin System. Journal of Cellular Physiology. 2010 Oct 13. [Epub ahead of print]
Kumar S, Seqqat R, Chigurupati S, Kumar R, Baker KM, Young D, Sen S, Gupta S. Inhibition of Nuclear Factor B (NF-B) Regresses Cardiac Hypertrophy by Modulating the Expression of Extracellular Matrix and Adhesion Molecules. Journal of Free Radical Biology and Medicine. 2010 Nov 1. [Epub ahead of print]
Verma SK, Lal H, Golden HB, Gerilechaogetu F, Smith M, Guleria R, Foster DM, Lu G, Dostal DE. Rac1 and RhoA Differentially Regulate Angiotensinogen Gene Expression in Stretched Cardiac Fibroblasts. Cardiovascular Research. 2010 Dec 3. [Epub ahead of print]
Chopra M, Das P, Golden H, Dostal DE, Watson LE, Sharma AC. Norepinephrine induces systolic failure and inhibits antiapoptotic genes in a polymicrobial septic rat model. Life Sciences. 2010 Dec 18;87(23-26):672-8. Epub 2010 Oct 7.
Book Chapters
Golden HB, Verma SK, Lal H, Foster DM, Ribeiro M, Mukhopadhyay S, Dostal DE. Mechanical Regulation of Stress-Activated MAP Kinases. Research Signpost. Book series “The Cardiac Fibroblast” edited by Neil Turner, 2011.
Workshops
David E. Dostal
Dr. Dostal Attended the Scientists Center for Animal Welfare (SCAW) workshop titled “The Evolution of Your IACUC: Promoting Science and Compliance”. It was sponsored by the University of Texas Health Sciences at San Antonio, TX on Dec 6-7, 2010.
Achievements
Honey Golden
Dr. Golden was awarded her Ph.D. at the commencement in College Station on December 17th, 2010 at the George Bush Presidential Library.
