May
From the Dean
Colleagues, Faculty, Staff and Students,
We have been quite busy this month with events, service activities and administrative undertakings, and I encourage you take a moment to read and share our good news.
On Saturday, May 21, the College of Medicine graduated 98 medical students at the Class of 2011 Commencement ceremony in Texas A&M’s Rudder Auditorium. For me, it was my first College of Medicine commencement, and for some of our long-serving faculty, it was their thirty-first such ceremony. By my count, that means that the College has turned more than 1,700 students into alumni in the past 34 years. Congratulations to the Class of 2011 for joining that number.
Five of our graduates were commissioned as officers in the United States military, specifically the Air Force and Navy, at a special ceremony before Commencement at the Sanders Corps of Cadets Center. Family and one of our very own faculty members pinned officers bars on the graduates. Certainly military medicine affords our students a special opportunity, and we honor and thank them for their commitment to serve.
Also at commencement, we presented the 2011 Graduate Research Excellence Award to Dr. Chen Chen. This award is given each year to a graduating Ph.D. or M.D.-Ph.D. student who has demonstrated independence, creativity and significant productivity in their graduate research with a high potential for success in a future research career. Dr. Chen trained with Dr. Jim Samuel in the Department of Microbial and Molecular Pathogenesis. The 2011 Helen Salyer Anderson Award was presented to Dr. Ramesh Kumar. Established by Frank G. Anderson, Jr., M.D., in 1980, the Anderson Award is given to an outstanding senior with the highest achievement in four years of medical school. Please join in our congratulations to Dr. Chen and Dr. Kumar.
The American Academy of Family Medicine recently honored the College of Medicine with a Top Ten Award for our continued contributions toward addressing the nation’s family medicine physician shortage and our efforts to produce family medicine and primary care doctors. Ten schools were recognized nationally, and ours was the only medical school in Texas to receive the award. I am exceedingly proud of the work of our faculty and staff to produce such a valuable human resource for the state and the nation.
Throughout April and May, students and staff gathered to thank, celebrate and honor the faculty who are the heart of the College of Medicine with annual Faculty Appreciation Dinners at each campus. Awards chosen entirely by the students were given for outstanding faculty and clerkships. A complete list of award winners can be found in “Faculty News,” and you can see photos from the Bryan-College Station, Round Rock and Temple campuses’ celebrations at the College of Medicine facebook page.
The Medical Research and Education Building (MREB) on the Bryan campus is now officially occupied. The Department of Microbial and Molecular Pathogenesis has moved in and is setting up their labs on the third floor. We will continue to work with the Health Science Center and the contractors to manage the moving of people and resources into the MREB as efficiently as possible.
We will officially welcome 200 students in the Class of 2015, our largest class ever, at the White Coat Ceremony on Monday, July 25, and I encourage you to attend the ceremony as able.
We have much to do in the coming months, and I thank you for your continued hard work and diligence.
Sincerely,
T. Samuel Shomaker, M.D., J.D.
The Jean and Thomas McMullin Dean of Medicine and
Vice President for Clinical Affairs for the Texas A&M Health Science Center
Dates to Remember
- M1 Welcome Weekend: Saturday, May 28, 10 a.m.-4 p.m., HPEB, Bryan campus
- Memorial Day Holiday for TAMHSC Employees: Monday, May 30
- Executive Committee Meeting: Thursday, June 2, 3-4 p.m., all locations
- Academic Council Meeting: Thursday, June 2, 4-5 p.m., all locations
- Basic Science Dept. Chairs Meeting: June 9, 12-1:30 p.m., HPEB 3047B, MEC 407C
- Dean’s Semi-Monthly Staff Meeting: June 14, 9-10:30 a.m., all locations
- Family Medicine Residency Graduation: Friday, June 24, more details soon
- DATE CHANGE Class of 2015 White Coat Ceremony: Monday, July 25, more details soon
College News
COM: Top 10 in US for family medicine
The American Academy of Family Medicine (AAFP) recently honored the Texas A&M Health Science Center (TAMHSC) College of Medicine with a Top Ten Award for the institution’s continued contributions toward addressing the nation’s family medicine physician shortage. The TAMHSC-College of Medicine was the only medical school in Texas to receive the award. See the full article at TAMHSC-News
PHOTO: Dr. Janice K. Smith from the Texas A&M Dept. of Family & Community Medicine accepts the award on behalf of the College of Medicine.
COM “Marches for Babies” at Annual Event
On Saturday, May 7, a team from the College of Medicine, including staff, faculty and family members, gathered with hundreds of participants at Wolf Pen Creek to “March for Babies” as part of the 2011 March of Dimes. See the full article at TAMHSC-News
PHOTO: College of Medicine faculty, staff and family members "march for babies" on foot, wheels and paws.
Web Content Providers: CMS Training Now Offered Monthly, Next Session June 1
For anyone who serves their department as a website content provider, the Texas A&M Health Science Center website content management system (CMS) training was recently modified to include hands-on, interactive exercises.
With the upcoming holiday in mind, CMS Training will not be held the last Friday of this month, but on Wednesday, June 1 from 9 a.m. until 12 noon in MSL-044, College Station. It’s a great opportunity to brush up on your content management skills and find out about useful features within Cascade Server 6.7. Please contact Cynthia Kauder, Technical Communication Specialist, if you would like to sign up for the upcoming session (contact information below).
OIT’s Web Services Group regular training sessions are held the last Friday of every month. It’s a great opportunity to brush up on your content management skills and find out about useful features within Cascade Server 6.7.
Register at http://training-cms.tamhsc.edu/
In addition, the Web Services Group maintains a CMS Training Site which provides users with quick reference sheets, tutorials, frequently-asked questions, and a thorough User Guide for Cascade Server 6.7. A new feature of the site includes step-by-step videos that show how to perform specific tasks within the CMS.
If you have any questions about registration or about the site referenced, please contact Cynthia Kauder at 979-436-0916
Faculty
Newell Rogers/S&W Receive $2M gift
Scott & White Healthcare in Temple, Texas has received an anonymous gift of $3.5 million. Two million dollars will go toward cancer cell research led by M. Karen Newell Rogers, Ph.D., director of the Center for Cell Death and Differentiation at Scott & White and the Texas A&M Health Science Center.
“This generous gift will further the advancement of critical cancer research, bridging the gap between research and the delivery of new therapies, said Dr. Newell Rogers. This gap often causes therapies to languish in laboratories for up to 14 years.” A gift like this reduces drug development time in half. More funds mean more resources for research. This gift will also fund construction of a tissue cell laboratory.
See the complete article at TAMHSC-News
Faculty Across Campuses Recognized at Appreciation Dinners
Throughout April and May, students on the Bryan-College Station, Round Rock and Temple campuses took time to thank and honor their faculty members with Faculty Appreciation Dinners and awards.
Bryan-College Station Awardees:
Outstanding Internal Medicine Faculty
Dr. William Pieratt
Outstanding Surgery Faculty
Dr. Bruce Hoak
Outstanding Obstetrics and Gynecology Faculty
Dr. William Price
Outstanding Pediatrics Faculty
Dr. Betty-Ann Svendsen
Outstanding Family Medicine Faculty
Dr. John Simmons
Outstanding Psychiatry Faculty
Dr. Darlene McLaughlin
Outstanding Emergency Medicine Faculty
Dr. Michael Spohn
Outstanding Fourth Year Faculty
Dr. Mark Brauer
Dr. James Kirby
Outstanding Faculty in Intensive Care Medicine
Dr. Scott Spencer
Best Clerkship: Surgery
O.C. Cooper Preceptors of the Year
Dr. Lane Miller
Dr. Gabriel Neal
Dr. Troy Simon
Dr. Randy Smith
Round Rock Awardees:
Family Medicine: Flint DeShazo, MD
Internal Medicine: Manual Jose, MD
Psychiatry: Virginia Garay, MD
Pediatrics: Daniel Richards, MD
OB/GYN: Michelle Irvin, MD
Surgery: Paul Buckley, MD
Temple Awardees:
At the Temple campus awards banquet, the graduating class of 2011 selected General Surgery as the Best Clerkship. We applaud Dr. Scott Thomas and Dr. Danny Little for their leadership.
Outstanding Clerkship Faculty were:
Emergency Medicine: Dr. Trey Morris
Family Medicine: Dr. Marc Via
General Surgery: Dr. Scott Thomas
Internal Medicine: Dr. Darla Lowe
Obstetrics and Gynecology: Dr. Kimberly Pilkington
Pediatrics: Dr. Michael Smith
Psychiatry: Dr. Phil Antunes
Thank you to each of these outstanding faculty for your commitment to quality undergraduate education.
Family Medicine Doc and Resident Present at Sports Med Annual Meeting
Kory Gill, D.O., Assistant Professor of Family & Community Medicine and Texas A&M Physician, presented a poster titled “Leg Swelling in a Division I Athlete,” and first-year Family Medicine Resident Laura Persky, M.D., presented a case study entitled “An Unusual Cause of Dysuria” at the American Medical Society for Sports Medicine's Annual Meeting in Salt Lake City in April.
In Print and On Air
Kory Gill, D.O., an assistant professor at Texas A&M Health Science Center College of Medicine and Texas A&M Physician, was quoted in a May 3 Health.com article on kids and sports injuries.
Russell Fothergill, MD, an assistant professor of obstetrics and gynecology at Texas A&M Health Science Center College of Medicine, was quoted in a May 2 Parents.com article about pregnancy side effects.
Carmen Ramirez, M.D., M.Sc., Assistant Professor of Internal Medicine and Texas A&M Physician, joined Brazos Valley This Morning on April 26 to talk about stroke symptoms and prevention.
Dr. Philip Houck, assistant professor of internal medicine at Texas A&M Health Science Center College of Medicine, was quoted in an April 19 HealthDay article about women taking calcium supplements and heart health risks.
Ian Murray, PhD, an assistant professor of neuroscience and experimental therapeutics at the Texas A&M Health Science Center College of Medicine, was quoted in an April 15 About.com article about treating high cholesterol and reducing the risk of Alzheimer's disease.
Students
GSO Hosts Successful 16th Annual Student Research Symposium
Sixty-one Texas A&M Health Science Center (TAMHSC) students presented their scholarly research on Friday, May 6 as part of the 16th Annual Graduate Student Organization (GSO) Student Research Symposium at the Health Professions Education Building on the TAMHSC Bryan campus.
By providing students an opportunity to showcase scholarly research in a collaborative, peer-reviewed structure, the Graduate Research Symposium is the only event of its kind that emphasizes a professional approach to the science behind medicine across all TAMHSC components.
See the full article at TAMHSC-News
M4 Meade Awarded Scholarship to travel to DC for AAP
Fourth-year student, Julia Meade, was selected as one of 10 scholarship awardees out of more than 30 applicants for the American Academy of Pediatrics Department of Federal Affairs’ Advocacy Training Session on Friday, May 6, 2011.
Toribio Awarded TMA Scholarship
Antonio Toribio was awarded the Texas Medical Association (TMA) Minority Scholarship at a presentation ceremony on Friday, May 13 in Houston during the TMA annual conference. The $5,000 scholarship will be used toward his tuition.
PHOTO: Pictured, left to right: Russ Kridel, M.D. – President, TMA Foundation; William Walton, M.D. – President, Bell County Medical Society; Antonio Toribio of Bryan; and Carolyn Evans, M.D. – Immediate Past Chair, TMA Board of Trustees.
Administration
Update: MREB Building Open
The Medical Research and Education Building (MREB) on the Bryan campus is now officially occupied. The Department of Microbial and Molecular Pathogenesis has moved in and is now busily unpacking and setting up their new labs on the third floor.
The Department Neuroscience and Experimental Therapeutics will move in stages, likely beginning in late May and ending in late June. The NEXT research labs will occupy the second and fourth floors, while the first floor contains administrative space for NEXT and the College of Medicine Office of Research and Graduate Studies, along with seminar rooms.
It has been a long and time consuming process from the design phase to the final occupancy of this new research facility, and I wanted to thank everyone who has been involved in this effort. MREB is an outstanding facility and should provide tremendous opportunities for research and education for the College of Medicine and the Health Science Center for decades to come.
Van G. Wilson, Ph.D.
Associate Dean for Research and Graduate Studies
Hannigan to Receive Education Award
Gale G. Hannigan, Ph.D., MLS, MPH, Director of Learning Resources, Professor & Librarian for Medical Informatics Education for the Texas A&M University Medical Sciences Library, will be awarded the 2011 Medical Library Association's Lucretia W. McClure Excellence in Education Award at the annual meeting in Minneapolis in May. The award, established in 1998 in honor of one of MLA's most respected members, honors outstanding practicing librarians or library educators in the field of health sciences librarianship and informatics who demonstrate skills in one or more of the following areas: teaching, curriculum development, mentoring, research, or leadership in education at local, regional, or national levels.
JAMP Receives Star Award from Coordinating Board
The Joint Admission Medical Program received the Star Award from the Texas Higher Education Coordinating Board (THECB) in November 2010. The award was presented to Kate Fallon, M.D., Senior Associate Dean for Student Affairs, and another medical school representative at the May 2, 2011 JAMP Council meeting. The Star Award was established in 2001 and recognizes public and independent institutions, groups and individuals for their exceptional contributions to the THECB’s Closing the Gaps by 2015 plan.
Web Content Providers: CMS Training Now Offered Monthly, Next Session June 1
For anyone who serves their department as a website content provider, the Texas A&M Health Science Center website content management system (CMS) training was recently modified to include hands-on, interactive exercises.
With the upcoming holiday in mind, CMS Training will not be held the last Friday of this month, but on Wednesday, June 1 from 9 a.m. until 12 noon in MSL-044, College Station. It’s a great opportunity to brush up on your content management skills and find out about useful features within Cascade Server 6.7. Please contact Cynthia Kauder, Technical Communication Specialist, if you would like to sign up for the upcoming session (contact information below).
OIT’s Web Services Group regular training sessions are held the last Friday of every month. It’s a great opportunity to brush up on your content management skills and find out about useful features within Cascade Server 6.7.
Register at http://training-cms.tamhsc.edu/
In addition, the Web Services Group maintains a CMS Training Site which provides users with quick reference sheets, tutorials, frequently-asked questions, and a thorough User Guide for Cascade Server 6.7. A new feature of the site includes step-by-step videos that show how to perform specific tasks within the CMS.
If you have any questions about registration or about the site referenced, please contact Cynthia Kauder at 979-436-0916Basic Science
MICROBIAL AND MOLECULAR PATHOGENESIS
Recent Publications
McCallan L, Corbett D, Andersen PL, Aagaard C, McMurray DN, Barry C, Thompson S, Strain S, McNair J. A new experimental infection model in ferrets based on aerosolized Mycobacterium
bovis. Vet Med International 2011: ID981410, 9 pp. (2011)
Presentations, Conferences and Meetings
Dr. Amminikutty Jeevan gave a talk on “Ultraviolet radiation (UVB) induces cellular and molecular changes in guinea pig skin” at the Texas Tuberculosis Researchers’ Symposium (TTRS) in UTMB, Galveston, TX on April 11th 2011.
Dr. Van Wilson attended the AAMC GRAND annual meeting in Washington, D.C., on April 28- May 1, 2011.
Dr. David McMurray traveled to Galveston on 10-11 April to attend the annual Texas TB Research Symposium at UTMB. He presented a talk entitled “TNFa in the guinea pig model of pulmonary TB: Dr. Jekyll and/or Mr. Hyde?”
MOLECULAR AND CELLULAR MEDICINE
Recent Publications
Bayless, K.J., and Johnson, G.A. (2011) Role of the Cytoskeleton in Formation and Maintenance of Angiogenic Sprouts. J. Vasc. Res. 48(5) 359-385. [Epub ahead of print]
Krause, U., Seckinger, A., and Gregory, C.A. (2011) Assays of Osteogenic Differentiation by Cultured Human Mesenchymal Stem Cells. Methods Mol Biol. 698:215-230.
Khushoo, A., Yang, Z., Johnson, A.E., and Skach, W.R. (2011) Ligand-Driven Vectorial Folding of Ribosome-Bound Human CFTR NBD1. Mol Cell. 41(6):682-692.
Heallen, T., Zhang, M., Wang, J., Bonilla-Claudio, M., Klysik, E., Johnson, R.L., and Martin, J.F. (2011) Hippo Pathway Inhibits Wnt Signaling to Restrain Cardiomyocyte Proliferation and Heart Size. Science. 332(6028):458-461.
Maxwell, S.A., Cherry, E.M., and Bayless, K.J. (2011) Akt, 14-3-3z, and Vimentin Mediate a Drug-Resistant Invasive Phenotype in Diffuse Large B-Cell Lymphoma, J. Leuk Lymphoma. 52 (5) 849-864. 2011 Feb. 16 [Epub ahead of print]
Pace, CN, Fu, H., Fryar, KL, Landua, J., Trevino, SR, Shirley, B A, Hendricks, MM, Immura, S., Gajiwala, K., Scholtz, J.M., and Grimsley, GR. (2011) Contribution of hydrophobic interactions to Protein Stabilty. J. Mol. Biol. 408(3) 514-528. 2011 Mar 4. [Epub ahead of print]
Xie, R., Nguyen, S., McKeehan, K., Wang, .F, McKeehan, W.L. and Liu, L. (2011) Microtubule-associated protein 1S (MAP1S) bridges autophagic components with microtubules and mitochondria to affect autophagosomal biogenesis and degradation. J. Biol. Chem. 286 (12) 10367-10377. 2011 Jan 24. [Epub ahead of print]
Presentations
Dr. L. Liu gave a poster presentation at the Keystone Symposia “Autophagy” held in Whistler, British Columbia, Canada on March 27-April 1, 2011. The title was “Roles of LRPPRC-C19ORF5-RASSF1A Complex in Regulation of Autophagy and Suppression of Hepatocarcinomas. Autophagy (D1)”.
Dr. Jun-yuan Ji attended the 52nd Annual Drosophila Research Conference on "Signal Transduction within the Nucleus" from March 30 to April 3, 2011 in San Diego, CA. He presented a poster entitled "Genetic analyses of CDK8-CycC functions in vivo ". The poster was co-authored by Qun Wang, Lauren Bridges, Larry Jiang, and Suzie Park.
Dr. Steve Maxwell attended the American Association for Cancer Research Conference in Orlando, FL from April 1 to April 6, 2011. Evan Cherry an MD/PhD student presented the poster entitled "Akt and vimentin mediate a drug-resistant phenotype in diffuse large B-cell lymphoma" at the meeting which was co-authors by Kayla Bayless, Jim Sacchettini and Steve Maxwell.
Dr. James Martin gave a presentation at the 9th Annual Spring Symposium of the Cardiovascular Developmental Biology Center (CDBC) on April 13-15, 2011 at the Medical University of South Carolina in Charleston, SC. The presentation was entitled “Hippo-signaling in heart development: a Hippo-Wnt connection.
Dr. Leyuan Liu presented a seminar entitled “Roles of C19ORF5 in Autophagy and Tumor Suppression” at: 1) Paul L Foster School of Medicine, Texas Tech University Health Science Center in El Paso, Texas on April 14, 2011 and 2) University of North Dakota School of Medicine and Health Sciences in Grand Forks, North Dakota on April 18, 2011.
Dr. Jun-yuan Ji presented a Genetics Seminar entitled "Context-specific functions of CDK8 in Drosophila" on April 28, 2011 at Texas A&M University.
Service
Dr. Sarah Bondos served as a judge for an Undergraduate Research Symposium at Rice University in Houston, TX on April 15, 2011.
Dr. Geoffrey Kapler served on the NSF Mechanisms of Inheritance Grant Review Panel on April 20, 2011 through April 22, 2011 in Washington, DC.
Honors and Awards
Dr. Arthur Johnson was invited to give the prestigious ASBMB Fritz Lipmann Lectureship at the American Society for Biochemistry and Molecular Biology annual meeting on April 11, 2011 in Washington, D.C. The title of his lecture was "Membrane Protein Biogenesis" The ASBMB awards this lectureship every other year to an individual for their conceptual advances in the biochemistry, bioenergetics or molecular biology field. The award was established by friends and colleagues of Nobel Prize winner Lipmann. Dr. Johnson was one of eleven award-winning scientists to be honored during the joint 2011 Experimental Biology meeting.
Grants
Dr. Gregory Bix was awarded a Texas Brain and Spine Institute Research grant with co-P.I. L. Gerard Toussaint for $15,000 to study the effects of Perlecan DV in Glioblastoma Multiforme from 3/11 - 3/12.
Dr. Gregory Bix was awarded a McNair Foundation Research award for $22,000 to study the potential therapeutic effects of Perlecan DV in Alzheimer's disease from 5/11 - 5/12.
Dr Robert Tsai was honored as a recipient of the Texas A&M Health Science Center Enhancement Grant award.
Dr. Fen Wang was awarded a CPRIT - Individual Investigator Award titled, “Activation of Prostate Cancer Stem Cells through Aberrant FGF Signaling”. The award is for $798,945. The grant period starts May 2011. Dr. Wallace McKeehan is also a Co-PI on Dr Fen Wang’s award with the CPRIT-Individual Investigator Award.
Jean Tien a GSBS student with the IBT, under the mentorship of Dr. Fen Wang of the IBT and Jingming Xu of the BCM received a DOD Training Grant. The grant is titled “Investigating Steroid Receptor Coactive 3 (SRC3) as a Potential Therapeutic Target for Treating Advanced Prostate Cancer”. Award total is $80,283. Grant period is 3/15/11 – 4/14/13.
News
Dr James Martin recently had an article in the New York Times under the Science Section, published on 4/25/2011, regarding his publication on “Hippo Pathway Inhibits Wnt Signaling to Restrain Cardiomyocyte Proliferation and Heart Size”.The article link is http://www.nytimes.com/2011/04/26/science/26heart.html
NEUROSCIENCE AND EXPERIMENTAL THERAPEUTICS
Dr. Diane Chico
Dr. Diane Chico attended the Southern Group on Education Affairs, “Leadership and Advocacy in Medicine” in Houston, TX April 14th through 16th.
Dr. George Chiou
Dr. George Chiou coordinated the teaching of the China Program Course 2011 from March 21st through May 24th. He functioned as COM representative, coordinator, and lecturer in conjunction with the Schools of Pharmacy and Rural Public Health. There were 7 other COM faculty members participating in this course as well.
Dr. Chiou has two manuscripts in press:
Shen, Y, Zhuang, P and Chiou, GCY, Effect of guanabenz on rat AMD models and rabbit choroidal blood flow, The Open Ophthalmology J. In press, (2011)
Zhuang, P, Shen, Y, Lin, BQ, Zhang, WY, and Chiou, GCY, effect of quercetin on formation of choroidal neovascularization (CNV) in age-related macular degeneration (AMD). Eye Science Journal, In press (2011)
Dr. David Earnest
Manuscripts accepted or in press:
Farnell, Y.F., Shende, V.R., Neuendorff, N., Allen, G.C., and Earnest, D.J. (2011) Immortalized cell lines for real-time analysis of circadian pacemaker and peripheral oscillator properties. Eur. J. Neurosci. 33: 1533-1540.
Burkeen, J.F., Womac, A.D., Earnest, D.J. and Zoran, M.J. Mitochondrial calcium signaling mediates rhythmic extracellular atp accumulation in suprachiasmatic nucleus astrocytes. J. Neurosci., accepted.
Dr. William Griffith
Grants Received
NIH R01AG041360, “Estrogens, ovarian aging and calcium channel modulation”, WH Griffith (PI, 20% effort), Sohrabji, F (co-investigator, 15% effort), Chen, W-J, (co-investigator, 10% effort), 4/15/2011-3/31/2016, $1,041,876 direct costs.
NIH R01- Subcontract, “Basal Forebrain and Cognitive Aging: Novel Experimental and Therapeutic Avenues”, J Bizon PI, WH Griffith co-investigator, $30,822, 3/1/2011-5/31/2011.
Dr. Gary McCord
Dr. McCord attended the Texas Radiological Society Annual Meeting in Austin April 8th through 10th.
Dr. Rajesh Miranda
Eric R. Strickland, Michelle A. Hook, Sridevi Balaraman, J. Russell Huie, James W. Grau, and Rajesh C. Miranda (2011) MicroRNA dysregulation following spinal cord contusion: implications for neural plasticity and repair. Neuroscience, In press.
Rajesh C. Miranda (2011) Commentary: Will analyzing the epigenome yield cohesive principles of ethanol teratology? Alcoholism: Clinical and Experimental Research, in press.
Dr. Rajesh Miranda presented a seminar to the Genetics Graduate Student Association titled, “Epigenetic Control of microRNA Function in Fetal Neural Stem Cells: Uncovering Novel Mechanisms of Ethanol Teratology”. He also presented a seminar at the Earnest Gallo Clinic and Research Center, University of California, San Fancisco titled, “microRNA Programming of Fetal Neural Stem Cell Maturation: Uncovering Novel Mechanisms of Fetal Growth and Ethanol Teratology”.
Currently Dr. Miranda is the Vice-President of the Fetal Alcohol Spectrum Disorders Study group, an affiliate of the Research Society on Alcoholism. He is currently engaged in the organization of the Annual Meeting.
Dr. D. Samba Reddy
Reddy DS, Rogawski MA (2011). Neurosteroids in the Treatment of Epilepsy. Book chapter In: Jasper’s Basic Mechanisms of the Epilepsies, Fourth Edition (Noebels JL, Avoli M, Rogawski MA, Olsen RW, Delgado-Escueta AV, eds), Oxford University Press (in press).
Gangisetty O and Reddy DS. Ovarian Cycle-Related Neurosteroid Regulation of GABA-A Receptor Subunit Plasticity in the Hippocampus Subfields. FASEB Journal, April 201125 (Meeting Abstract Supplement) lb410.
Drs Murray and Sohrabji
Ian V.J. Murray Joseph F. Proza, Farida Sohrabji and John M. Lawler (2011) Vascular and metabolic dysfunction in Alzheimer's disease: A review. Exp. Biol Med, In Press
SYSTEMS BIOLOGY AND TRANSLATIONAL MEDICINE
Communiqués
Dr. Mariappan Muthuchamy chaired the Experimental Biology 2011 Symposium “Linking Integrin Adhesion and Mechanotransduction of Myocardial Function,” Washington, DC, April 12, 2011.
Luke Potts, MD/PhD student received a National Eye Institute Travel Grant for $750 for the upcoming Association for Research in Vision and Ophthalmology (ARVO) meeting in Fort Lauderdale, Florida, May 1-5, 2011. Luke will give an oral presentation at the meeting.
Dr. David Zawieja presided over the annual Microcirculatory Society meeting as President and chaired the session “Microcirculatory Society President’s Symposium,” Washington, DC, April 12, 2011.
Publications
Davis MJ, Rahbar E, Gashev AA, Zawieja DC, Moore JE Jr. Determinants of valve gating in collecting lymphatic vessels from rat mesentery. Am J Physiol Heart Circ Physiol. 2011 Apr 1. [Epub ahead of print]. PMID: 21460194.
Kojima C, Zhang Y, Zimmer,WE. Intronic DNA elements regulate androgen-dependent expression of the murine Nkx3.1 gene. Gene Expression 15:89-102, 2011.
Nagai T, Bridenbaugh EA, Gashev AA. Aging-associated alterations in contractility of rat mesenteric lymphatic vessels. Microcirculation. 2011 Apr 5. [Epub ahead of print]. PMID: 21466607
Presentations
Dr. Andreea Trache gave an invited presentation at the 241st American Chemical Society National Meeting & Exposition, “Membrane Mechanics and Dynamics” Session, Anaheim, California, March 28-30, 2011. The title of the presentation was “Real time mechanically induced cellular remodeling.”
Dr. Andreea Trache gave a presentation at the University of North Texas Health Science Center, Fort Worth, Texas, March 25, 2011. The title of the presentation was “Mechanical signaling induces adaptive remodeling in vascular smooth muscle cells.”
Experimental Biology 2011, Washington, DC, April 9-13, 2011.
Dr. A. G. Bohlen, Dr. Olga Gasheva, and Dr. David Zawieja presented an abstract titled “Heterogeneous production and influences of NO along the lymphatic endothelium.”
Dr. Anatoliy A. Gashev presented an abstract titled “Signs of aging-related inflammation and adaptive reserves of aged mesenteric lymphatic vessels.”
Dr. Anatoliy A. Gashev, Tony J. Akl, Dr. Takashi Nagai, and Dr. Gerard L. Coté presented a poster titled “Contractility and flow in aged mesenteric lymphatic vessels.”
Dr. Anatoliy A. Gashev, Dr. Takashi Nagai, Tony J. Akl, Dr. Sangeetha Thangaswamy, Victor Chatterjee, Dr. Gerard L. Cote, and Dr. Eric A. Bridenbaugh presented a poster titled “Signs of agingrelated inflammation and adaptive reserves of aged mesenteric lymphatic vessels.”
Dr. Anatoliy A. Gashev, Dr. Sangeetha Thangaswamy, Dr. Eric A. Bridenbaugh, Dr. Takashi Nagai, and Victor Chatterjee presented a poster titled “Oxidative stress, inflammation and function of aged lymphatic vessels.”
David W. Howell, Dr. Richard P. Metz, Dr. Natasa Popovic, and Dr. Emily Wilson presented an abstract titled “Transforming growth factor beta signaling in Marfan Syndrome.”
Dr. Lih Kuo gave a presentation titled “Selective activation of ROCK2 isoform contributes to vasomotor regulation of retinal arterioles.”
Dr. Richard P. Metz, Dr. Natasa Popovic, David Howell, and Dr. Emily Wilson presented an abstract titled “The role of Smad3 in TGF beta signaling in mouse aorta and smooth muscle cells.”
Dr. Takashi Nagai and Dr. Anatoliy A. Gashev presented a poster titled “Adenylate cyclase: role in regulation of contractility of mesenteric lymphatic vessels in adult and aged rats.”
Dr. Tam L. Nguyen, Dr. Ranjeet M. Dongaonkar, Dr. Joanne Hardy, Dr. Randolph H. Stewart, and Dr. Emily Wilson presented an abstract titled “Short-term functional adaptation of bovine mesenteric lymphatic vessels to partial occlusion.”
Dr. Nasir Uddin, Dr. Olga Gasheva, and Dr. David Zawieja presented an abstract titled “Nitric oxide dependent cellular signaling in cultural lymphatic smooth muscle cells.”
Dr. Wei Wang and Dr. David Zawieja presented an abstract titled “Histological study of APC in rat mesenteric prenodal, postnodal collecting lymphatics and thoracic duct.”
Dr. Xin Wu, Dr. Gerald A. Meininger, and Dr. Mariappan Muthuchamy presented an abstract titled “Feedback mechanisms linking regulation of ECM-integrin adhesion with myofilament activation.”
Scott Zawieja, Dr. Wei Wang, Dr. Zhanna Nepiyushchikh, Dr. Xin Wu, Dr. David Zawieja, and Dr. Mariappan Muthuchamy presented an abstract titled “Rat mesenteric lymphatics undergo remodeling and have altered contractility and calcium sensitivity in a model of metabolic syndrome.”
Dr. David Zawieja gave a presentation at the annual Microcirculatory Society meeting, Washington, DC, April 10, 2011. The title of the presentation was “Immune cells in the microcirculation.”
Professional Activities
Hailin Chen attended a training course taught by Edward Tufte titled “Presenting data and information.” The course was held in Austin, Texas, April 6, 2011.
Dr. Warren E. Zimmer participated in the Oklahoma Center for the Advancement of Science and Technology (OCAST) study section in Oklahoma City, Oklahoma, April 16-19, 2011.
Dr. Warren E. Zimmer attended the Society for Experimental Biology and Medicine (SEBM) Council Meetings and directed the SEBM Young Investigator Career Roundtable, Washington, DC, April 10, 2011.
Dr. David Zawieja participated in the NIH Study Section ZRG1 F10A “Physiology and Pathobiology of Cardiovascular and Respiratory Systems,” San Francisco, California, March 20-23, 2011.
Grants
Dr. Emily Wilson (Co-PI) and Dr. Jonathan Friedman (Co-PI) received a $15,000 Texas Brain and Spine Institute grant for the period 04/01/11-03/31/12. The title of the grant is “Culture and characterization of vascular smooth muscle cells from intracranial aneurysms.”
Clinical Science
DIVISION OF INVESTIGATIVE PATHOLOGY
DR. ALEXZANDER ASEA
Peer-Reviewed Publications
Vareed SK, Bhat VB, Thompson C, Vasu VT, Fermin D, Hyungwon C, Creighton CJ, Gayatri S, Lan L, Putluri N, Thangjam GS, Kaur P, Shabahang M, Giri JG, Nesvizhskii AI, Asea A, Cashikar AG, Rao A, McLoughlin J, Sreekumar A. Metabolites of purine nucleoside phosphorylase (NP) in serum have the potential to delineate pancreatic adenocarcinoma. PLoS ONE 2011; 6: 1-11.
Presentations/Meetings/Workshops
“Latest Research on a Cure for Breast Cancer” 1st Annual Catch a Cure Fishing Tournament,
April 23, 2011, Broxton, Marine, Belton, TX
“Translational Research Activities in the Division of Investigative Pathology” Sacchettini Lab,
Interdisciplinary Life Sciences Building (ILSB), April 22, 2011, College Station, TX
“Modulation of Anti-Tumor Effector Mechanisms via Hsp27” Society for Thermal Medicine
Annual Conference, April 29-May 2, 2011, New Orleans, LA
“Role of Heat Shock Proteins in the Prevention of Amylin Aggregation in Type 2 Diabetes
Mellitus” Society for Thermal Medicine Annual Conference, April 29-May 2, 2011, New Orleans, LA
Posters/Exhibit
“Development of an Effective Hsp72-Her2 Fusion Protein Vaccine.” Zheng H, Kaur P, Abdulrahman KB, Asea A. Society for Thermal Medicine Annual Conference, April 29-May 2, 2011, New Orleans, LA
“Molecular Characteristics of Triple-Negative Breast Cancer Stem Cells: Role of Hsp72-Containing Exosomes.” Kaur P, Abdulrahman KB, Krishnan S, Asea A. Society for Thermal Medicine Annual Conference, April 29-May 2, 2011, New Orleans, LA
Articles Reviewed
International Journal of Cancer
Journal of Biological Chemistry
Notable Accomplishments
Session Chair, “Thermally Augmented Immuno-, Chemo- and Radiosensitization” at the Society for Thermal Medicine Annual Conference, April 29-May 2, 2011, New Orleans, LA
Conferences Attended
Society for Thermal Medicine Annual Conference, April 29-May 2, 2011, New Orleans, LA
DR. PUNIT KAUR
Peer-Reviewed Publications
Vareed SK, Bhat VB, Thompson C, Vasu VT, Fermin D, Hyungwon C, Creighton CJ, Gayatri S, Lan L, Putluri N, Thangjam GS, Kaur P, Shabahang M, Giri JG, Nesvizhskii AI, Asea A, Cashikar AG, Rao A, McLoughlin J, Sreekumar A. Metabolites of purine nucleoside phosphorylase (NP) in serum have the potential to delineate pancreatic adenocarcinoma. PLoS ONE 2011; 6: 1-11.
Presentations/Meetings/Workshops
“Latest Research on a Cure for Breast Cancer” 1st Annual Catch a Cure Fishing Tournament,
April 23, 2011, Broxton, Marine, Belton, TX
“Translational Research Activities in the Division of Investigative Pathology” Sacchettini Lab,
Interdisciplinary Life Sciences Building (ILSB), April 22, 2011, College Station, TX
“Molecular Characteristics of Triple-Negative Breast Cancer Stem Cells: Role of Hsp72-Containing Exosomes,” Kaur P, Abdulrahman KB, Krishnan S, Asea A. Society for Thermal Medicine Annual Conference, April 29-May 2, 2011, New Orleans, LA
Posters/Exhibits
“Development of an Effective Hsp72-Her2 Fusion Protein Vaccine,” Zheng H, Kaur P, Abdulrahman KB, Asea A. Society for Thermal Medicine Annual Conference, April 29-May 2, 2011, New Orleans, LA
Notable Accomplishments
Co-Session Chair, “Thermally Augmented Immuno-, Chemo- and Radiosensitization” at the Society for Thermal Medicine Annual Conference, April 29-May 2, 2011, New Orleans, LA
PAOLA ROSAS
Abstracts Accepted/Presented
Abstract accepted at the 16th Annual COM GSO Student Research Symposium, Texas A&M, April 11th, 2011: “Role of Heat Shock Proteins in the Prevention of Amylin Aggregation in Type 2 Diabetes Mellitus”
Abstract accepted at the 2011 Society of Thermal Medicine Annual Meeting: “Role of Heat Shock Proteins in the Prevention of Amylin Aggregation in Type 2 Diabetes Mellitus”
Presentations/Meetings/Workshops
Journal club presentation at the Center for Cell death and differentiation, April 8th 2011
INTERNAL MEDICINE
Executive Summary of Scholarly ActivityScott & White/Texas A&M HSC COM |
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In order to generate an accurate count of scholarly products within the Department of Internal Medicine, all scholarly products are counted only once and are not reported for every faculty member involved. For the purposes of this departmental report, a scholarly product will be counted under the first author’s division or program only. If the first author is not in the Department of Internal Medicine, credit will be assigned to the highest author in IM. For March 2011, Department of Medicine divisions and programs reported the following scholarly activity: |
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Total Numbers |
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4 |
Peer-reviewed publications |
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20 |
Manuscripts – In review/accepted/in press |
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3 |
Abstracts accepted/presented |
|
2 |
Book chapters |
|
1 |
Editor - Book |
|
1 |
Grants received |
|
1 |
Grant submitted |
|
1 |
Reviewer – Grants |
|
7 |
Presentations |
|
2 |
Workshops |
|
5 |
Posters/exhibits |
|
6 |
Lectures |
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11 |
Articles reviewed – Peer-reviewed journals |
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1 |
Research projects |
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1 |
Educational Projects |
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8 |
Notable accomplishments |
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Reported by Division |
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Allergy |
Nothing reported for March 2011 |
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Cardiology |
See pages that follow for list of publications, etc. |
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2 |
Publications |
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2 |
Book Chapters |
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1 |
Editor - Book |
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Cardiology- Molecular |
Nothing reported for March 2011 |
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Endocrinology |
Nothing reported for March 2011 |
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Executive Health |
Nothing reported for March 2011 |
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Gastroenterology |
Nothing reported for March 2011 |
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Gastroenterology – Lab |
See pages that follow for list of publications, etc. |
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2 |
Publications |
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4 |
Manuscripts |
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1 |
Research Project |
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1 |
Poster/Exhibit |
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2 |
Lectures |
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2 |
Articles Reviewed |
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2 |
Notable accomplishments |
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General Internal Medicine |
See pages that follow for list of publications, etc. |
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|
Posters/Exhibits
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Geriatrics |
See pages that follow for list of publications, etc. |
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1 |
Manuscript |
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1 |
Abstract |
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1 |
Notable accomplishments |
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Hematology/Oncology |
See pages that follow for list of publications, etc. |
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1 |
Manuscript |
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1 |
Presentation |
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Hospital Medicine |
Nothing reported for March 2011 |
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Manuscripts
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Infectious Disease |
Nothing reported for March 2011 |
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Nephrology |
See pages that follow for list of publications, etc. |
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1 |
Manuscript |
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1 |
Presentation |
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4 |
Lectures |
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Nephrology Lab |
See pages that follow for list of publications, etc. |
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5 |
Manuscripts |
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1 |
Articles Reviewed |
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Pulmonary Disease |
See pages that follow for list of publications, etc. |
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1 |
Presentation |
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Manuscripts
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Rheumatology |
Nothing reported for April 2011 |
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Reported by Program/Center |
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Center for Applied Health Research (CAHR), Temple |
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CAHR Cores |
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Health Outcomes Core |
See pages that follow for list of publications, etc. |
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5 |
Manuscripts- Accepted/In Review/In press |
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2 |
Abstracts |
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2 |
Presentations |
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|
2 |
Posters and Exhibits |
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3 |
Articles Reviewed |
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1 |
Grants submitted |
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1 |
Grants reviewed |
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3 |
Notable accomplishments |
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Office of System Data Metrics |
Nothing reported for March 2011 |
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Program on Aging and Care |
Nothing reported for March 2011 |
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Office of Medical Education, Evaluation & Research Development (OMEERD) |
See pages that follow for list of publications, etc. |
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1 |
Manuscript – In press
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2 |
Workshops |
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Posters/Exhibits
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2 |
Notable Accomplishments |
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Patient Engagement and Safety Research Program (PESRP) |
See pages that follow for list of publications, etc. |
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1 |
Grant received/submitted |
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2 |
Presentations |
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1 |
Poster/Exhibit |
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1 |
Educational Project |
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Community Research Center for Senior Health |
Nothing reported for March 2011 |
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Medical Education (UME/GME) Residency, fellowship and medical student activities and scholarly products |
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2 |
Manuscripts |
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Publications – Peer-Reviewed
Cardiology
1. Patel MR, Wolk MJ, Allen J, Dehmer, GJ, Brindis RG. The privilege of self regulation. The role of appropriate use criteria. J Am Coll Cardiol 2011;57:1557-9.
2. Culp BC, Mock JD, Ball TR, Chiles CD, Culp Jr WC. The pocket echocardiograph: A pilot study of its validation and feasibility in intubated patients. Echocardiography.2011;Feb 17.doi: 10.1111/j.1540-8175.2010.01370.x.[Epub ahead of print]
Gastroenterology Lab
1. Functional Analysis of microRNAs in Human Hepatocellular Cancer Stem Cells. Meng F, Glaser SS, Francis H, Demorrow S, Han Y, Passarini JD, Stokes A, Cleary JP, Liu X, Venter J, Kumar P, Priester S, Hubble L, Stoloch D, Sharma J, Liu CG, Alpini G. J Cell Mol Med. 2011 Feb 25. doi: 10.1111/j.1582-4934.2011.01282.x. [Epub ahead of print]
2. Turner R, Lozoya O, Wang Y, Cardinale V, Gaudio E, Alpini G, Mendel G, Wauthier E, Barbier C, Alvaro D, Reid LM. Hepatology. 2011 Mar;53(3):1035-45. doi: 10.1002/hep.24157.PMID: 21374667 [PubMed - in process]
Manuscripts Accepted/In Review/In press
CAHR – Health Outcomes Core
1. Noel PH, Zeber JE, Pugh MJ, Finley EP, Parchman ML. – In Review - “Post-deployment health care needs in small community-based primary care clinics”. [Primary Care & Community Health]
2. Arar N, Noel PH, Zeber JE, Parchman ML. – In Review - “Implementing quality improvement in small, autonomous primary care practices: implications for the patient centered medical home” [Health Care Management Review]
3. Copeland LA, Zeber JE – In Review - “Ethnicity and race variations in receipt of vascular surgery among depressed veterans” [Depression Research & Treatment]
4. Zeber JE, Miller AL, Copeland LA, McCarthy JF, Zivin K, Valenstein M, Greenwald D, Kilbourne AM. – In Press - “Medication adherence, ethnicity and the influence of psychosocial and financial barriers” [Administrative Policy of Mental Health] March 2011
5. Copeland LA, Ettinger AB, Zeber JE, Gonzalez JM, Pugh MJ. – In Press - “Psychiatric and medical admissions among elderly patients with new-onset epilepsy” [BMC Health Services Research] March 2011
CAHR – OMEERD
1. Colbert CY, Ogden PE, Ownby AR, Bowe C. Systems-Based Practice in Graduate Medical Education: Systems Thinking as a Foundational Construct. Teaching and Learning in Medicine. In press. March 2011.
GI Lab
1. Meng F, Glaser SS, Francis H, Demorrow S, Han Y, Passarini JD, Stokes A, Cleary JP, Liu X, Venter J, Kumar P, Priester S, Hubble L, Stoloch D, Sharma J, Liu CG, Alpini G. Functional Analysis of microRNAs in Human Hepatocellular Cancer Stem Cells. J Cell Mol Med. 2011. PMID: 21352471
2. Francis H. “Inhibition of histidine decarboxylase ablates the autocrine tumorigenic effects of histamine in human cholangiocarcinoma”, accepted pending revision, Gut
3. Francis H, & Alpini, et al. HEP-11-0339 “The H4HR agonist, clobenpropit, suppresses human cholangiocarcinoma progression by disruption of EMT and tumor metastasis” Accepted pending revision, Hepatology
4. G Alpini, S Glaser, J-P Zhang, H Francis, Y Han, J Gong, A Stokes, T Francis, N Hughart, L Hubble, S-M Zhuang, and F Meng. Regulation of placenta growth factor by microRNA-125b in hepatocellular cancer. J Hepatol, 2011, in press.
Geriatrics
1. Emily R. Smith, MSPH, Nicole M. Webb, MA, Elaine H. Bailey, PhD, Amie Ragan, PhD, Alan B. Stevens, PhD. The Cornell Scale for Depression in Dementia (CSDD): Structured for Use in Clinical Research. In review at Aging and Mental Health.
Hematology/Oncology
1. Schimmer A, Herr W, Hänel M, Borthakur G, Frankel AE, Horst HA, Martin S, Kassis J, Desjardins P, Seiter K, Fiedler W, Noppeney R, Giagounidis A, Jacob C, Jolivet J, Tallman M, Koschmieder S. The addition of AEG35156 XIAP antisense oligonucleotide to reinduction chemotherapy does not improve remission rates in patients with primary refractory AML in a randomized phase II study. Clin Lymphoma Myeloma Leuk 2011. in press
Medical Education – UME/GME
1. Colbert CY, Myers JD, Cable CT, Ogden PE, Mirkes C, McNeal T, Skeen S. Residents become systems thinkers in resident clinic: Effects of the CCORE experience. Academic Medicine. In review March 2011.
Internal Medicine Residency Program
2. Moran J, Colbert CY, Hull J, Song J, Rajan S, Arroliga A, Reddy S. Factors associated with 30-day, same-case hospital readmissions. J Hosp Med. In review. March 2011. Dr. Moran is a PGY-3 resident.
Nephrology Lab
1. Chiasson VL, Talreja D, Young KJ, Chatterjee P, Banes-Berceli A, Mitchell BM. FK506 binding protein 12 deficiency in endothelial and hematopoietic cells decreases regulatory T cells and causes
2. Chiasson VL, Quinn MA, Young KJ, Mitchell BM. PKCbetaII-mediated phosphorylation of eNOS threonine 495 mediates the endothelial dysfunction induced by tacrolimus. J Pharmacol Exp Ther 2011;(in press).
3. Chiasson VL, Munshi N, Young KJ, Mitchell BM. Pin1 deficiency increases endothelial nitric oxide synthase serine 116 phosphorylation, endothelial dysfunction, and blood pressure. Hypertension 2011;(in 2nd review
4. Chiasson VL, Jones KA, Mahajan A, Young KJ, Mitchell BM. Endothelial cell TGF-beta receptor activation causes tacrolimus-induced renal arteriolar hyalinosis. Kidney Int 2011;(in review).
5. Chatterjee P, Chiasson VL, Young KJ, Chatterjee V, Mitchell BM. Interleukin-10 deficiency exacerbates Toll-like receptor 3-induced preeclampsia-like symptoms in mice. Hypertension 2011;(in 3rd review).
Nephrology
1. Is the Effect of MPA Intolerance on Graft Outcome Influence by Calcineurin Inhibitor Exposure? Outcome Analysis of the Mycophenolic Renal Transplant (MORE) Registry: Wang J, Narayanan M, et al. In review, CJASN.
Abstracts Accepted/Presented
CAHR-Health Outcomes Core
1. Zeber, JE Ph.D. A Systematic Literature Review of Behavioral Risk Factors Associated with Initial Medication Adherence accepted by the International Society for Pharmacoeconomics and Outcomes Research (Baltimore) for presentation in May 2011.
2. Copeland LA, PhD. “Epidemiology of Three Common Surgeries in Veterans with Serious Mental Illness” accepted for poster presentation at Academy Health’s 2011 Annual Research Meeting on June 12-14, 2011, Seattle WA.
Geriatrics
1. Stevens A. Abstract accepted to Academy Health National Conference in June.
Book Chapters
Cardiology
1. Taneja T, Huang SKS. Irrigated and Cooled-Tip Radiofrequency Catheter Ablation. In: Catheter Ablation of Cardiac Arrhythmias, 2nd Edition, Huang SKS, Wood MA Editors, Elsevier Saunders, Philadelphia, PA, 2011, pages 32-42.
2. Huang SKS. Atrioventricular Junction Ablation and Modification for Heart Rate Control of Atrial Fibrillation. In: Cathether Ablation of Cardiac Arrhythmias, 2nd Edition, Huang SKS, Wood MA Editors, Elsevier Saunders, Philadelphia, PA, 2011, pages 351-358
Cardiology Editors- Book Chapters
Editor - Books
1. Huang SKS, Wood MA. Editors. Catheter Ablation of Cardiac Arrhythmias, 2nd Edition, Elsevier Saunders, Philadelphia, PA, 2011
Research Projects
Gastroenterology Lab
1. Alpini. Autocrine/Paracrine Regulation of Intrahepatic Bile Duct Growth. VA Merit Award
Regulation of bile duct growth in bile duct ligated rats. NIH
Growth Regulation of the Intrahepatic Biliary Tree. NIH
Role of Sensory Neuropeptides in the Regulation of Biliary Function
Presentations
Pulmonary
1. Beckendorf. Pulmonary Critical Care Journal Club presentation with Fellow Dr. Julio Novelo. Treatment options of Stage 1 Lung Cancer. Monday, March 28, 2011
Nephrology
1. Concepcion. “Anemia Management”: Renal Physicians Association Annual Meeting, March 18, 2011, Washington, DC. (national)
Hematology/Oncology Division
1. Wong L. Invited to University of Kentucky: Updates on Gastric Cancer -3/10/11.
CAHR- Health Outcomes Core
1. Copeland LA, Noel PH. “Using VA Corporate Data Warehouse to Access Vitals”, VA Information Resource Center Cyber-seminar, March 17, 2011
2. Zeber JE. “The Cost-Benefit Policy Implications of a Medication Copayment Increasement in Veterans with Schizophrenia” at the 10th Workshop for Mental Health Policy and Economics, Venice, Italy, March 27, 2011
CAHR- Patient Safety Core
1.Wehbe-Janek H. Standardized Patients, Simulating the Patient, Family Member or Friend: Education and Research. Temple Rotary Club Presentation, March 14, 2011. Local.
2.P Saenz, L Warren, H Wehbe-Janek, A Hubbard, D Austin. Multidisciplinary Pediatric Code Training Using Simulation. Pediatric Resident Research Day. Children’s Hospital at Scott & White. March 2011; Local presentation
Posters/Exhibits
GI LAB
1. F Meng, T Francis, G Alpini, D Staloch, and H Francis. The H4HR agonist, clobenpropit, inhibits migration, invasion and epithelial mesenchymal transition (EMT) during cholangiocarcinoma development. Presentation at AACR meeting, Orlando, FL, April 2-5, 2011.
Geriatrics
1. Karon Phillips, Emily Smith, Alan Stevens. Psychologist in Primary Care poster –– Presented at HMORN National Conference – Boston, MA, 3/21-3/25/11. Poster.
CAHR - Health Outcomes Core
1. Copeland LA, Godwin, Kjar, MacCarthy A, Myers D “Readmission and 30-day Mortality Among CAP Patients in Two Systems of Care” poster presented at the HMORN 2011 Annual Meeting, Boston, MA, March 23-25, 2011. Poster presentation.
2. Zeber JE, Godwin DA, Copeland LA, Mahajan BS, McNeal CJ. “Outcomes of Cardiovascular Events in Two Systems of Care” poster presented at the HMORN 2011 Annual Meeting, Boston MA, March 23-25, 2011. Poster presentation.
CAHR - PESRP, OMEERD & General Internal Medicine
1. Wehbe-Janek H, McMahon E, Hochhalter A, Sklar L, Colbert CY. Pilot Study of the Preparing for the Best Transitional Care Preparatory Intervention; HMORN Conference, Boston, MA, March 22-25. Poster presentation.
Workshops
CAHR-Office of Medical Education, Evaluation & Research Development
1. Colbert CY. “Systems Thinking: A Foundation for Systems-Based Practice Education and Assessment.” Selective offered during Harvard Macy Institute’s “A Systems Approach to Assessment in Health Professions Education” course, Boston, MA, March 13-18, 2011. Presented 3/14-3/17 to an international audience of health professions educators.
2. Colbert CY. Workshop: “Curriculum Vitae 101: Your CV as Both a Process and a Product.” Workshop offered as part of the Professional Development Series, Office of Medical Education, Evaluation & Research Development, DOM. March 31, 2011. Audience: Endocrinology and GI fellows/faculty.
Lectures
GI Lab
1. Alpini. Talk entitled “VEGF regulation of biliary growth" Gastroenterology, University of then Studies of Rome “La Sapienza” March 14, 2011.
2. Alpini. Talk entitled “Neuroendocrine regulation of biliary growth " Human AnatomyUniversity of the Studies of Rome “La Sapienza” March 14, 2011.
Nephrology
1. Enoch Agunanne, MD: “Diuretics; Chronic Kidney Disease”, Nephrology Journal Club, March 23, 2011, Scott & White Temple. (fellows & senior staff)
2. Multiple Cholesterol Emboli Syndrome”: Nephrology Core Lecture, March 16, 2011, Scott & White Temple. (audience: fellows & senior staff)
3. Hoang-Lan Nguyen, DO: “Renin Angiotensin System”, Renal Physiology Conference, March 10, 2011, Scott & White Temple. (fellows & senior staff)
4. Geetha Seerangan, MD: “Encapsulating Peritoneal Sclerosis”, Nephrology Morbidity & Mortality Conference, March 2, 2011, Scott & White Temple. (fellows & senior staff)
Articles Reviewed – Peer-Reviewed Journals
Nephrology Lab
1. Mitchell B. Hypertension - 4
GI_Lab
1. Francis H. Cancer Letters – 1
Francis H. BMC – 2
CAHR- Health Outcomes Core
1. Copeland LA. Clinical Schizophrenia & Related Psychoses - 1
2. Copeland LA. Medical Care – 1 one article
3. Zeber J. American Journal of Public Health – 2 articles
Grants – Received
CAHR-PESRP Core
1. Wehbe-Janek H. OMeGA Medical Grants Association, (Rahm, PI); $15,000. Evaluation of the Clinician-Patient Communication Workshop for Enhancing Communication and Interpersonal Skills in an Orthopaedic Surgery Residency Program; 6 month grant
Grants – Submitted
CAHR-Health Outcomes Core
1. Reif S Ph.D. – PI, co-investigators Copeland LA, Potter J, Perloff JE, Larson MJ, Wang CP.“Pain and Addiction: Pain Care, Behavioral Healthcare Utilization, and Outcomes” submitted to the National Institute on Drug Abuse # R01 DA031282.
Grants – Reviewed
CAHR-Health Outcomes Core
1. Copeland LA. Scott & White Research Grants Program Mentor Award. Reviewed grant March 25, 2011
Educational Projects
CAHR-PESRP
1. Wehbe-Janek H. , Ph.D., CAHR – PESRP. Developed the Research Ethics Selective for Medical Humanities.First offering of the selective began March 22, 2011.
Notable Accomplishments: Faculty News, Appointments, Nominations
GI Lab
1. Francis H. Appointment to Assistant Professor of Internal Medicine, Texas A&M HSC COM, effective March 2011.
2. Francis H. Attendance by teleconference of an NIH study session, HBPP, April 5, 2011.
Geriatrics
1. National Cancer Institute Study Section, R13 Special Emphasis Review, Bethseda, MD – March 27th-28th.
CAHR- Health Outcomes Core
1. Parchman ML, Zeber JE, Palmer R. (2010), “Participatory decision making, patient activation, medication adherence and control of risk factors for complications for type-2 diabetes.” Annals of Family Medicine, 8(5):410-7. One of the most read articles in the Annals of Family Medicine in January 2011. Notified March 2011.
2. Zeber JE. Chair - Medical Comobordity Symposium, 10th Workshop for Mental Health Policy and Economics, Venice, Italy, March 27, 2011
3. Copeland LA. On March 29, 2011, Drs Chester Davis and Bernie Winkle in the Office of the Medical Inspector of the Veterans Health Administration (VHA) called Dr Copeland to update her on the impact of her 2006 paper published in Medical Care (Copeland LA; Zeber JE; Rosenheck RA; Miller AL. Unforeseen inpatient mortality among veterans with schizophrenia. Med Care 2006;44(2):110-116. PMID 16434909). Based on Dr Copeland’s finding that patients with schizophrenia are at increased risk of unforeseen inpatient death, and that this risk is multiplied when a patient has been out of contact with the healthcare system for a 12-month period, the VHA’s Office of the Medical Inspector initiated an outreach program for all such “lost” veterans across the country. Mortality rates were confirmed to be lower for those brought back into care. The outreach activity is being made into a Directive for use across VHA.
CAHR - Office of Medical Education, Evaluation & Research Development
1. Colbert CY. Visiting faculty member, Harvard Macy Institute’s “A Systems Approach to Assessment in Health Professions Education,” Boston, MA, March 13-18, 2011. International audience of health professions educators.
2. Myers JD. Appointed chair of the E-Learning Task Force, Association of Program Directors in Internal Medicine, March 2011.
INTERNAL MEDICINE RESEARCH
Giafranco Alpini, PhD.
- Attendance by teleconference of an NIH study session, HBPP, April 5, 2011.
A Omenetti, L M Bass, RA Anders, M G Clemente, H Francis, D Guy, S McCall, S S Choi, G Alpini, K B Schwarz, A M Diehl, and P F Whitington. Hedgehog activity, epithelial-mesenchymal transitions, and biliary dysmorphogenesis in biliary atresia. Hepatology 53: 1246-58, 2011.
On behalf of the Governing Board of the American Association for the Study of Liver Diseases (AASLD), Dr. Gianfranco Alpini will continue serving as an abstract reviewer member for the “Biliary Physiology, Transport, Cholangiocyte Biology, Experimental Cholestasis:Organic Ion Transport, Bilirubin Metabolism; Cholesterol, Lipid, Bile Acid Metabolism; Cholangiocyte Biology;Experimental Cholestasis” review committee.
Internal Medicine Research Day, April 7, 2011
Basic Science Poster Awards
3rd Place - Yuyan Han, M.S - “MELATONIN INHIBITS IN VIVO CHOLANGIOCARCINOMA GROWTH BY ENHANCED BILIARY EXPRESSION OF SEROTONIN N-ACETYLTRANSFERASE (AANAT) THE CENTRAL ENZYME INVOLVED IN MELATONIN SYNTHESIS; NOVEL EVIDENCE FOR THE MANAGEMENT OF CHOLANGIOCARCINOMA BY AN AUTOCRINE LOOP”
Poster presentations
F Meng, T Francis, G Alpini, D Staloch, and H Francis. The H4HR agonist, clobenpropit, inhibits migration, invasion and epithelial mesenchymal transition (EMT) during cholangiocarcinoma development. Presented at AACR meeting, Orlando, FL, 2011.
H Francis, P Onori, R Mancinelli, A Franchitto, F Meng, J Venter, A Renzi, C J Meininger, E Gaudio, and G Alpini. H1 histamine receptor agonists accelerate the regrowth of the biliary tree after 70% hepatectomy by increased biliary VEGF expression. Presented at EB meeting, Washington DC, MD, 2011.
DeMorrow lab
Monoamine oxidase A expression correlates with cholangiocarcinoma tumor grade and survival and is suppressed via IL-6-driven hypermethylation of the promoter. Li Huang, Gabriel Frampton, Li-Jian Liang, Sharon DeMorrow. Presented at the 102nd Annual Meeting of the American Association for Cancer Research, Orlando, Florida April 2-6 2011
The novel cannabinoid receptor GPR55, inhibits cholangiocarcinoma growth. Sharon DeMorrow, Gabriel Frampton, Matthew Quinn, Li Huang. Presented at the Experimental biology meeting, Washington DC 9-13th April 2011
SURGERY
“Ronald B. Kuppersmith, MD, FACS of the Department of Surgery was recently elected as a Fellow of The Triological Society. He also was a visiting speaker at the Instanbul Society of Otolaryngology Head and Neck Specialists in April 2011; presented the Annual John Young Lecture and was a visiting professor at the University of Minnesota, was a visiting professor at the University of Cincinnati Department of Otolaryngology, and the Indiana University Department of Otolaryngology-Head and Neck Surgery. He was also the Keynote Speaker at the “Best of ORL 2010” in Paris, France in October 2010, and was an invited speaker at the Severence (Yonsei) da Vinci Live 2010 Symposium in Seoul, Korea.”
Here are some recent publications to list as well:
Kuppersmith RB, Holsinger FC. Robotic Thyroid Surgery: An Initial Experience with North American Patients. The Laryngoscope. 2011: 121(3): 521-526.
Grisel JJ, Atkins JH, Fleming DJ, Kuppersmith RB. Clinical Evaluation of a Bioresorbable Implant for Medialization of the Middle Turbinate in Sinus Surgery. International Forum of Allergy & Rhinology. 2011: 1(1): 33-37.
Perrier ND, Randolph GW, Inabnet WB, Marple BF, Vanheerden J, Kuppersmith RB. Robotic Thyroidectomy: a Framework for New Technology Assessment and Safe Implementation.Thyroid. 2010 Dec;20(12):1327-32.
Kuppersmith RB, Schams ST, Rosenfeld RM. Extracts from the Cochrane Library: Tonsillectomy for Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Cervical Adenitis Syndrome (PFAPA) . Otolaryngology-Head and Neck Surgery. 2010: 143, 473-475.
Holsinger FC, Terris DJ, Kuppersmith RB. Robotic Thyroidectomy: Operative Technique Using a Transaxillary Approach without CO2 Insufflation . Otolaryngologic Clinics of North America. 2010: 43:381-388.ACADEMIC MEDICINE
Division of Molecular Cardiology
Presentations
Kenneth M. Baker
Dr. Baker presented the talk entitled “Intracardiac Intracellular Angiotensin System in Diabetes” during the Session on Intracrine Renin-Angiotensin System: A New Paradigm in Cardiovascular and Renal Control, at The American Physiological Society Experimental Biology 2011 Meeting, Washington DC, 9-13 April, 2011.
Professional Service
David E. Dostal
Dr. David Dostal has accepted an invitation from the National Institutes of Health Center for Scientific Review to serve as a member of the Cardiac Contractility, Hypertrophy, and Failure Study Section. His three year term will begin July 1, 2011.
Dr. David Dostal participated as a panel member for National American Heart Association’s Molecular Signaling 3 Peer Review Committee on April 6, 2011.
Sudhiranjan Gupta
Dr. Gupta reviewed 12 AHA Grants in the Cardiac BCT2 National Review section.
Dr. Gupta reviewed 3 papers for J Cell Physiology, 1 for Free Radical Research, and 1 review article for Expert Opinion on Therapeutic Targets.
Dr. Gupta reviewed one Scientific Grant from the Lytmos Foundation.
Publications (Published)
Miller T, Yang F, Wise CE, Meng F, Priester S, Munshi MK, Guerrier M, Dostal DE, Glaser SS. Simvastatin stimulates apoptosis in cholangiocarcinoma by inhibition of Rac1 activity. Dig Liver Dis., 43(5):395-403, 2011.
Publications (Accepted)
Sopko N, Qin Y, Finan A, Dadabayev A, Chigurupati S, Qin J, Penn MS, Gupta S. ILK-a-Parvin (PIP) complex in human dilated cardiomyopathy. Accepted in PLoS One.
Book Chapters
Honey B. Golden, Suresh K. Verma, Hind Lal, Marcelo Ribero, Swagoto Mukhopadhyaya, Donald M. Foster and David E. Dostal. Mechanical Regulation of Stress-activated MAP kinases. In The Cardiac Fibroblast, Editor: Neil A. Turner, Research Signpost, pp. 978-81, 2011.
Awards
Internal Medicine Research Day, April 7, 2011, Basic Science Poster Awards
Colby A. Souders, B.S. received 1st place for his poster entitled: “c-Myc Guides Cardiac Angiogenesis in a Cell and Gene Specific Manner”
Stephanie L.K. Bowers, B.S. received an honorable mention for her poster entitled: "IL-6 Plays a Key Role in Cell-Cell and Cell-ECM Interactions that Mediate Angiogenesis in the Heart”
Irina T. Nizamutdinova, M.D., Ph.D. received an honorable mention for her poster entitled: “Retinoic Acid Protects Against Hyperglycemia-Induced Cardiomyocyte Apoptosis through Inhibition of NF-KB Signaling”
