Entry Year: 2000
Graduation Year: 2007
Currently: PGY-3, Orthopedic Surgery, University of Toronto
Email Address: e.qamirani@utoronto.ca
Undergraduate: McMurry University, B.S. Biology
Laboratory: Dr. Lih Kuo, Systems Biology and Translational Medicine
Thesis: "C-reactive protein impairs coronary microvascular function"

Abstracts and Presentations

• Qamirani, E.,  T.W. Hein, and L. Kuo.  "Sodium azide dilates coronary arterioles via barium-sensitive inward rectifier potassium channels." Circulation 108: IV-226, 2003.
• Qamirani, E., W. Wang, L. Kuo, and T.W. Hein.  "C-reactive protein inhibits endothelium-dependent nitric oxide-mediated dilation in coronary arterioles: roles of superoxide and vascular NADPH oxidase."
• Qamirani, E., W. Wang, L. Kuo, and T.W. Hein. "C-reactive protein inhibits endothelium-dependent nitric oxide-mediated dilation in coronary arterioles via p38 kinase and NADPH oxidase activation." Circulation III-73, 2004.
• Razavi, H., E. Qamirani, L. Kuo, and T.W. Hein. "Coronary arteriolar dilation to K+ is mediated by activation of smooth muscle Kir2.1 channels and Na+/K+ ATPase." FASEB J. 19:LB55, 2005.
• Qamirani, E., W. Wang, L. Kuo, and T.W. Hein. "C-reactive protein inhibits endothelium-dependent nitric oxide-mediated dilation in coronary arterioles by activating the LOX-1 receptor and NADPH oxidase." FASEB J. 19:A1265, 2005.
• Razavi, H, E. Qamirani, L. Kuo, and T.W. Hein.  "Coronary arteriolar dilation to K⁺: role of smooth muscle K_ir2.1 channels and Na⁺/K⁺ ATPase." Circulation. 112:II-132, 2005.
• Qamirani, E., Y. Ren, L. Kuo, and T.W. Hein.  "C-reactive protein activates LOX-1 and inhibits prostacyclin-mediated dilation of coronary arterioles." Circulation. 112:II-217, 2005.
• Hein T.W., E. Qamirani, R.D. Shipley, Y. Ren, X. Xu  and L. Kuo. "C-reactive protein inhibits endothelium-dependent prostacyclin synthase-mediated dilation of coronary arterioles: role of peroxynitrite."  FASEB J. 21:900.12, 2007.
• Chaput, C., R. Barber, D. Dominguez, E. Qamirani, and M. Rahm. "Injury Severity Score (ISS) Correlates with Surgical Approach in Subaxial Cervical Trauma. " The Spine Journal 7:129S-130S, 2007

Publications

• Bock B.C., P.O. Vacratsis, E. Qamirani, and K.A. Gallo, KA. "Cdc42-induced activation of the mixed-lineage kinase SPRK in vivo. Requirement of the Cdc42/Rac interactive binding motif and changes in phosphorylation." J. Biol. Chem. 275:14231-14241, 2000.
• Han, T.H., E. Qamirani, A.G. Nelson, D.R. Hyduke, G. Chaudhuri, L. Kuo, L and J.C. Liao. "Regulation of nitric oxide consumption by hypoxic red blood cells." Proc. Natl. Acad. Sci. 100:12504-12509, 2003.
• Qamirani, E.,  Y. Ren, L. Kuo, and T.W. Hein. "C-reactive protein inhibits endothelium-dependent nitric oxide-mediated dilation in coronary arterioles by activating p38 kinase and NADPH oxidase." Arterioscler. Thromb. Vasc. Biol., 25:995-1001, 2005.
• Qamirani, E., H. Razavi, X. Wu, M.J. Davis, L. Kuo, L and T.W. Hein. "Sodium Azide Dilates Coronary Arterioles via Activation of Inward Rectifier K+ Channels and Na+-K+ ATPase." Am. J. Physiol. Heart. Circ. Physiol. 290:H1617-H1623, 2006.
• Hein, T.W., E. Qamirani, Y. Ren, L. Kuo. "C-reactive protein impairs coronary arteriolar dilation to prostacyclin synthase activation: role of peroxynitrite."  J Mol Cell Cardiol. 47:196-202, 2009.

Awards

• Caroline tum Suden Award for Meritorious Research (American Physiological Society), 2005.
• 1st Place Research Award, Cardiovascular Research Institute Poster Competition, Texas A&M Health Science Center, 2005.
• Research Grant from the Osteosynthesis and Trauma Care Foundation, Switzerland, 2009.  "Effect of multiple and delayed administrations of cell-based vascular endothelial growth factor (VEGF) gene therapy administrations on a segmental bone defect".  E. Qamirani, Principal Investigator.