Entry Year: 1996
Graduation Year: 2005
Currently: Rabson Fellow, National Cancer Institute
Residency: Anatomic Pathology, National Institutes of Health, Bethesda MD
Email Address: milesgeo@mail.nih.gov
Undergraduate: Southwestern University
Laboratory: Dr. Hagan Bayley, Medical Biochemistry and Genetics
Thesis: "On the structure and assembly of Staphylococcal leukocidin: A study of molecular architecture of beta-barrel pore-forming toxins"
Research Interests: Protein engineering, membrane pore-forming proteins

Publications:

• Miles, G, Cheley, S, Braha, O and Bayley, H. "The staphylococcal leukocidin bicomponent toxin forms large ionic channels." Biochemistry 40:8514-22, 2001.
• Miles, G, Movileanu, L and Bayley, H. "Subunit composition of a bicomponent toxin: staphylococcal leukocidin forms an octameric transmembrane pore." Protein Sci 11:894-902, 2002.
• Miles, G, Bayley, H and Cheley, S. "Properties of Bacillus cereus hemolysin II: a heptameric transmembrane pore." Protein Sci 11:1813-24, 2002.
• Jayasinghe L, Miles, G and Bayley, H. "Role of the amino latch of staphylococcal alpha -hemolysin in pore formation: a co-operative interaction between the N terminus and position 217." J Biol Chem 281:2195-2104, 2006.
• Miles, G, Jayasinghe, L and Bayley, H. "Assembly of the bi-component leukocidin pore examined by truncation mutagenesis." J Biol Chem 281:2205-2214, 2006.

Awards:

• NSF Young Scholar Award, National Science Foundation (RCD-8850140).
• Graduate Student Research Symposium, Texas A&M Health Science Center, 2nd prize poster, 2001.
• Graduate Student Research Symposium, Texas A&M Health Science Center, 3rd prize oral presentation, 2002.