Entry Year: 2007
Currently: M3
Email Address: gwroddy@medicine.tamhsc.edu
Undergraduate: Texas A&M University, B.S. Biomedical Science
Laboratory:  Dr. Darwin Prockop, MD, PhD
Research Interests: Therapeutic applications adult stem/progenitor cells (mesenchymal stem cells; MSCs)
Thesis: Adult stem/progenitor cells and their secreted proteins for the treatment of ocular disease

Abstracts and Presentations

• Roddy, G.W., J.Y. Oh, H.S. Choi, R.H. Lee, U. Krause, R.H. Rosa, and D.J. Prockop.  Adult stem/progenitor cells (MSCs) and their secreted proteins reduce inflammation in the cornea following chemical injury.  Abstract accepted for the National MD/PhD Student Conference, Keystone CO.  July 2010.
• Oh J.Y., G.W. Roddy, R.H. Lee, K. Claypool, and D.J. Prockop.  The anti-inflammatory and the anti-apoptotic proteins from adult stem/progenitor cells (MSCs) protect corneal epithelial progenitors from injury by preventing apoptosis and suppressing inflammation.  International Society for Stem Cell Research (ISSCR).  San Francisco, CA.  June 2010.
• Rosa, R.H., G.W. Roddy , U. Krause, and D.J. Prockop.  Feasibility Study on Intravitreal and Subretinal Delivery of Adult Stem/Progenitor Cells (MSCs) for Retinal Repair.  The Association for Research in Vision and Ophthalmology (ARVO).  Fort Lauderdale, FL.  May 2010.
• Oh J.Y., G.W. Roddy, H.S. Choi, R.H. Lee, K. Claypool, and D.J. Prockop. Adult stem/progenitor cell-derived factors protect corneal epithelial progenitors by promoting proliferation and preventing apoptosis.  The Association for Research in Vision and Ophthalmology (ARVO).  Fort Lauderdale, FL.  May 2010.  
• Roddy, G.W, J.Y. Oh, H.S. Choi, R.H. Lee, U. Krause, R.H. Rosa, and D.J. Prockop.  The anti-inflammatory protein TSG-6, produced by activated adult stem/progenitor cells (MSCs), reduces inflammation in the cornea following chemical injury.  GSBS Student Research Symposium, College Station TX.  April 2010.
• Roddy, G.W. and A.C. Lekven.  What the Zebrafish has to Tell us About Wnt6.  The Fourth Biennial Texas and Southern Plains Zebrafish Conference, College Station, TX. June 2007.
• Roddy, G.W. and K.J. Bayless.  Abnormal Enzymatic Turnover of TIMP-3 in Sorsby’s Fundus Dystrophy and Macular Degeneration.  Texas A&M University Student Research Week, College Station, TX. March 2007.
• Shivapurkar, N., V. Stastny, G.W. Roddy, H.F. Liu, J.D. Minna, and A.F. Gazdar.  Development of quantitative PCR assays for methylation of novel tumor suppressor genes and their application as a biomarker assay for multiple types of cancers. American Association of Cancer Research (AACR), Las Angeles, California. April 200
• Roddy, G.W., K.K. Svoboda, R. West, M. Roberts, S. Senkayi, and E.K. Harrington. Proliferation Protein Ki-67 is Increased in PTH Exposed Primary Cartilage. American Academy of Dental Research (AADR), Orlando, Florida.  April 2006
• R. West, E.K. Harrington, G.W. Roddy, M. Patel, and K.K. Svoboda.  Activation of the PTH/PTHrP Receptor Increases Cyclin-D1 mRNA Levels. American Academy of Dental Research (AADR), Orlando, Florida.  April 2006.

Publications

• Roddy GW, Rosa Jr RH, Youn Oh J, Ylostalo JH, Bartosh TJ Jr, Choi H, Lee RH, Yasumura D, Ahern K, Nielsen G, Matthes MT, Lavail MM, Prockop DJ. "Stanniocalcin-1 Rescued Photoreceptor Degeneration in Two Rat Models of Inherited Retinal Degeneration", Mol Ther. 2012 Jan 31. doi: 10.1038
• Roddy GW, Oh JY, Lee RH, Bartosh TJ, Ylostalo J, Coble K, Rosa RH Jr, Prockop DJ. "Action at a distance: systemically administered adult stem/progenitor cells (MSCs) reduce inflammatory damage to the cornea without engraftment and primarily by secretion of TNF-α stimulated gene/protein 6", Stem Cells. 2011 Oct 29(10):1572-9. doi: 10.1002
• Oh JY, Roddy GW, Choi H, Lee RH, Ylöstalo JH, Rosa RH Jr, Prockop DJ. "Anti-inflammatory protein TSG-6 reduces inflammatory damage to the cornea following chemical and mechanical injury", Proc Natl Acad Sci U S A. 2010 Sep 28;107(39):16875-80. Epub 2010 Sep 13.
• Harrington E.K., G.W. Roddy, R .West, and K.K. Svoboda.  Parathyroid Hormone/Parathyroid Hormone-Related Peptide Modulates Growth of Avian Sternal Cartilage via Chondrocytic& Proliferation. Anatomical Record, 290(2):155–167, 2007.