Distribution of MSCs for Academic Research
BACKGROUND
The Texas A&M Health Science Center College of Medicine Institute for Regenerative Medicine at Scott & White has received a grant funded by the NIH to provide well-characterized human adult stem cells, rat stem cells, and mouse stem cells to academic researchers worldwide upon request. The adult stem cells are the plastic adherent cells from bone marrow referred to as colony forming units-fibroblastic, mesenchymal stem cells or multipotent mesenchymal stromal cells (MSCs). The cells are isolated, expanded and extensively characterized in our own laboratories. We provide a detailed protocol for expansion of the cells. We also provide a Product Specification Sheet on each lot of cells that indicates many of the characteristics of the cells, including the proliferation rate we have observed in expanding the frozen cells, data on colony forming units, and differentiation into mineralizing cells, adipocytes and chondrocytes. For an example of the Product Specification Sheet for human MSCs, see the sample spec sheet of characteristics.
HUMAN ADULT STEM CELLS
Human adult stem cells are distributed in a single vial, containing approximately one million frozen adult stem cells. Also, available are lentivirus transduced MSCs containing fluorescent proteins such as GFP (cytoplasmic expression), MitoRed or MitoBlue (mitochondrial expression) and some MSCs with a combination of GFP and either MitoRed or MitoBlue. Individuals interested in obtaining cells must first complete and return two signed originals of a Texas A&M Health Science Center Materials Transfer Agreement to the address below. There is a negotiable handling charge of $150 for the vial of human adult stem cells. The charge can be waived in hardship situations.
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RAT ADULT STEM CELLS
The Texas A&M Health Science Center College of Medicine Institute for Regenerative Medicine at Scott & White also supplies samples of adult rat stem cells to academic researchers. Currently, stem cells from adult male Lewis rats are available. Samples of these cells are provided as a single vial containing approximately 300,000 to 500,000 frozen cells. Individuals interested in obtaining cell samples must first complete and return two signed originals of a Texas A&M Health Science Center Materials Transfer Agreement to the address below. There is a negotiable charge of $100 for the vial of rat stem cells. The charge can be waived in hardship situations.
MOUSE ADULT STEM CELLS
The Texas A&M Health Science Center College of Medicine Institute for Regenerative Medicine at Scott & White also supplies samples of mouse stem cells to academic researchers. Stem cells from 3 strains of mice are available: C57Bl/6J, and 2 GFP-expressing strains (C57Bl/6-TgN(ACTbEGFP)1Osb and C57BL/6-Tg(UBC-GFP)30Scha/J). Samples of these cells are provided as a single vial containing approximately 300,000 to 500,000 cells. Individuals interested in obtaining cell samples must first complete and return two signed originals of a Texas A&M Health Science Center Materials Transfer Agreement to the address below. There is a negotiable charge of $100 for the vial of mouse stem cells. The charge can be waived in hardship situations.
SHIPPING
Recipients are responsible for payment of shipping charges. The Texas A&M Health Science Center College of Medicine Institute for Regenerative Medicine at Scott & White offers two methods of shipping cells; either on dry ice or in a liquid nitrogen shipper. Payment for shipping must be by certified check, Visa, Mastercard, or your FedEx account. We cannot accept purchase orders.
INFORMATION
For further information and a Material Transfer Agreement, please contact MSC Distribution at:
Institute for Regenerative Medicine at Scott & White
Texas A&M Health Science Center College of Medicine
5701 Airport Rd., ModC
Temple, TX 76503
Phone: (254) 771-6814
Fax: (254) 771-6839
Email: msc@medicine.tamhsc.edu
