Martha's Health Clinic was started in 1994 by two Texas A&M medical students, Eric Wilke and Eric Beshires, who saw a need for better health care for the homeless population in Temple, TX. They began their outreach by taking blood pressures once a week at Martha's Homeless Shelter. Soon, these students realized that the people of Martha's Shelter needed more extensive medical care than they were able to obtain.

Through a joint effort of dedicated medical students and Martha's Kitchen/Shelter, a free student-run clinic for the homeless was established. The success of this project was due, in large part, to the support of Deacon Fred Banderas, who was serving as chairman of Martha's Kitchen/Shelter at that time. Within a year from opening, Martha's Health Clinic had expanded from one room to an entire wing. Since then, medical students have continued to provide quality healthcare to the homeless of Temple and Bell County.