Garret M. Ihler

Garret M. Ihler

Adjunct Professor


Department of Molecular and Cellular Medicine
Phone: (979) 845-2726

Education and Post-Graduate Training

Garret Ihler received his B.S. in Chemistry from California Institute of Technology in 1961, his Ph.D. in Biochemistry and Molecular Biology from Harvard University in 1967 in the shared laboratory of James D. Watson and Walter Gilbert where he worked on E. coli RNA Polymerase and transcription in Bacteriophage lambda. He also worked on Lambda in the laboratory of Matthew Meselson. He did his postdoctoral work in the Department of Biological Chemistry at the Harvard Medical School in the laboratory of Charles Thomas. While at Harvard Medical School, he devised a procedure for the isolation of genes and isolated the first gene, lacZ. He joined the faculty at the University of Pittsburgh School of Medicine in 1969 and later received his M.D. degree from the University of Pittsburgh in 1976. He came to Texas A&M as Professor and Head of the Department of Medical Biochemistry & Genetics in 1977. He is currently holder of the Tom and Jean McMullin Chair of Genetics, a member of the Faculty of Genetics, director of the Laboratory for the Study of Cell Surfaces, has been a faculty senator from the College of Medicine, and served on the TAMU Senate Executive Committee. He is MiniReviews editor of FEMS Microbiology Letters. He has taught medical students in courses in Medical Biochemistry and Medical Genetics at the University of Pittsburgh and at TAMU. He has also taught undergraduate and graduate courses in molecular biology and molecular genetics. Dr. Ihler retired after 27 years with the university.

Publications

  • Ihler, G., and Chami-Stemmann, H. (2003) 7-oxo-DHEA and Raynaud’s Phenomenon. Medical Hypotheses. 60(3), 391-397.
  • Verma, A., Ihler, G.M. (2002) “Activation of Rac, Cdc42 and Other Downstream Signaling Molecules by Bartonella bacilliformis during Entry into Human Endothelial Cells,” Cellular Microbiology. 4,557-569.
  • Verma, A., Davis, G.E., and Ihler, G.M. (2001) "Formation of stress fibres in human endothelial cells infected with Bartonella bacilliformis is associated with altered morphology, impaired migration and defects in cell morphogenesis," Cellular Microbiology. 3,169-180
  • Derrick, S.C., and Ihler, G.M. (2001) “Deformin, A Substance Found in Bartonella bacillifiormis Culture Supernatants, is a Small, Hydrophobic Molecule with an Affinity for Albumin. Blood Cells, Molecules, and Diseases. 27,1013-1019.
  • Verma, A., Davis, G.E., and Ihler, G.M. (2000) "Infection of Human Endothelial Cells with Bartonella bacilliformis Is Dependent of Rho and Results in Activation of Rho," Infection and Immunity. 68, 5960-5969.